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ArticleHypertension research : official journal of the Japanese Society of Hypertension2026

Association of hypertension specialist treatment with blood pressure control in Japanese primary care: The J-DOME study.

Daigoro Hirohama, Shigeru Shibata, Narumi Eguchi, Tsuguru Hatta, Kazuomi Kario, Tomohiro Katsuya, Kazuo Kobayashi, Akira Nishiyama, Mitsuhiko Noda, Yoichi Nozato and 5 more

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Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Daigoro HirohamaDivision of Nephrology, Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Shigeru ShibataDivision of Nephrology, Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Narumi EguchiJapan Medical Association Research Institute, Tokyo, Japan.
Tsuguru HattaHatta Medical Clinic, Kyoto, Japan.
Kazuomi KarioDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan.
Tomohiro KatsuyaKatsuya Clinic, Hyogo, Japan.
Kazuo KobayashiCommittee of Kidney and Electrolyte Disease, Japan Physicians Association, Tokyo, Japan.
Akira NishiyamaDepartment of Pharmacology, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Mitsuhiko NodaDepartment of Diabetes, Metabolism and Endocrinology, Ichikawa Medical Center, International University of Health and Welfare, Chiba, Japan.
Yoichi NozatoDepartment of Geriatric and General Medicine, Toyonaka Municipal Hospital, Osaka, Japan.
Kensuke SasakiDepartment of Nephrology, Hiroshima University Hospital, Hiroshima, Japan.
Keisuke ShinoharaDepartment of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan.
Emi UshigomeFaculty of Arts and Sciences, Kyoto Institute of Technology, Kyoto, Japan.
Kei AsayamaDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan. kei@asayama.org.
J-DOME Research Analysis Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although hypertension is a major contributor to cardiovascular complications, real-world blood pressure (BP) control in primary care and the role of hypertension specialists remain incompletely characterized. We evaluated BP control and associated factors using the Japan Medical Association Database of Clinical Medicine (J-DOME), a nationwide primary care registry. This cross-sectional study included patients with hypertension registered in 2024, categorized by treatment by specialists certified by the Japanese Society of Hypertension. Multivariable logistic regression identified factors associated with achieving office BP < 130/80 mmHg. Among 2663 patients (43.6% women; mean age, 71.4 years), 545 were treated by hypertension specialists. Mean BP was 134.4/74.8 mmHg, and the mean number of antihypertensive drugs was 1.6. Systolic BP was similar between specialist- and non-specialist-treated patients (135.1 vs. 134.2 mmHg; p = 0.28), whereas diastolic BP (76.1 vs. 74.5 mmHg; p = 0.0060) and the number of drugs (1.9 vs. 1.6; p < 0.0001) were higher in the specialist-treated group. Target BP achievement rate was lower in the specialist-treated group (30.8% vs. 37.3%; p = 0.0058), however, this difference was not observed among patients aged <75 years (33.2% vs. 35.4%; p = 0.55). The multivariable-adjusted model revealed that diabetes mellitus (odds ratio [OR], 1.32; 95% confidence interval [CI], 1.08-1.61) and a higher number of drugs (OR per additional drug, 1.12; 95% CI, 1.04-1.22) were associated with higher target achievement, whereas overweight (OR, 0.70; 95% CI, 0.58-0.85), obesity (OR, 0.57; 95% CI, 0.42-0.77), and specialist treatment (OR, 0.77; 95% CI, 0.61-0.96) were associated with lower achievement. Office BP control remains suboptimal in Japanese primary care. Lower achievement among specialist-treated patients despite more drugs may reflect the concentration of difficult-to-control hypertension in specialist care. Continued efforts to improve hypertension management, particularly in patients with obesity, are warranted.

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Blood pressureHypertensionHypertension specialistJ-DOMEPrimary care

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.