Evidence map›Paper›PMID 42826006›Full record

ReviewJournal of physiology and biochemistry2026

Myokines and mitochondrial function in cardiometabolic diseases.

Jairo E Saavedra, Jaime Gallo-Villegas, Juan C Calderón

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of physiology and biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jairo E SaavedraPhysiology and Biochemistry Research Group-PHYSIS, Faculty of Medicine, University of Antioquia, Medellín, Colombia.ORCID http://orcid.org/0000-0002-4814-0673
Jaime Gallo-VillegasSports Medicine Postgraduate Program, and Research Group in Medicine Applied to Physical Activity and Sports-GRINMADE, Faculty of Medicine, University of Antioquia, Medellín, Colombia.ORCID http://orcid.org/0000-0002-6296-5110
Juan C CalderónPhysiology and Biochemistry Research Group-PHYSIS, Faculty of Medicine, University of Antioquia, Medellín, Colombia. jcalderonv00@yahoo.com.ORCID http://orcid.org/0000-0002-8695-6972

Funding

CODI-University of Antioquia 2024-76710Planning Office University of Antioquia E01792-B and ES03180101
6 · The paper itself

Abstract

Cardiometabolic diseases (CMD) encompass a group of disorders sharing a common pathophysiology that increases the risk of cardiovascular disease and mortality. Key events underlying CMD pathophysiology include insulin resistance, low-grade inflammation, altered hormonal and myokine profiles, and mitochondrial dysfunction. The latter manifests as reduced mitochondrial mass and oxidative function, increased oxidative stress, altered Ca

Indexed as

Cardiovascular DiseasesMitochondriaMitochondria, MuscleMuscle, SkeletalMyokinesAnimalsFibronectinsHumansInsulin ResistanceOxidative StressFibronectinsFNDC5 protein, humanMyokinesHealthy lifestyleMitochondriaMyokinesObesitySkeletal muscle

Identifiers

PMID42826006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.