Evidence map›Paper›PMID 42825947›Full record

ArticleVeterinary research communications2026

Dietary Bixa orellana leaf meal enhances growth performance, haemato-biochemical responses of Amur carp (Cyprinus carpio haematopterus) following Edwardsiella tarda challenge.

Divyanshu Kumar Upadhyay, Avdhesh Kumar, Suresh Chandra, Tarang Kumar Shah, Ajay Kumar Upadhyay, Ashutosh Mishra, Akansha Khati, Rini Joshi, Diksha Arya, Priyanka Rani and 1 more

Abstract read
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Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Divyanshu Kumar UpadhyayDepartment of Aquaculture, College of Fisheries, Govind Ballabh Pant University of Agriculture and Technology (GBPUA&T), Pantnagar, Uttarakhand, 263145, India.
Avdhesh KumarDepartment of Aquaculture, College of Fisheries, Govind Ballabh Pant University of Agriculture and Technology (GBPUA&T), Pantnagar, Uttarakhand, 263145, India.
Suresh ChandraFish Resource Management Division, ICAR- Central Institute of Coldwater Fisheries Research, Bhimtal, Uttarakhand, India.
Tarang Kumar ShahDepartment of Fisheries, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh, 176061, India. kunnushah4545@gmail.com.
Ajay Kumar UpadhyayDepartment of Veterinary Public Health & Epidemiology, College of Veterinary & Animal Sciences, Govind Ballabh Pant University of Agriculture and Technology (GBPUA&T), Pantnagar, Uttarakhand, 263145, India.
Ashutosh MishraDepartment of Aquatic Environment Management, College of Fisheries, Govind Ballabh Pant, University of Agriculture and Technology (GBPUA&T), Pantnagar, Uttarakhand, 263145, India.
Akansha KhatiDepartment of Aquaculture, College of Fisheries, Govind Ballabh Pant University of Agriculture and Technology (GBPUA&T), Pantnagar, Uttarakhand, 263145, India.
Rini JoshiFish Resource Management Division, ICAR- Central Institute of Coldwater Fisheries Research, Bhimtal, Uttarakhand, India.
Diksha AryaDepartment of Aquaculture, College of Fisheries, Govind Ballabh Pant University of Agriculture and Technology (GBPUA&T), Pantnagar, Uttarakhand, 263145, India.
Priyanka RaniDepartment of Aquaculture, College of Fisheries, Govind Ballabh Pant University of Agriculture and Technology (GBPUA&T), Pantnagar, Uttarakhand, 263145, India.
Madhu SharmaDepartment of Fisheries, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh, 176061, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effects of dietary Bixa orellana leaf meal on the growth performance and haemato-biochemical responses of Amur carp (Cyprinus carpio haematopterus) against Edwardsiella tarda infection. A total of 180 fish (9.23 ± 0.82 g) were equally distributed into four groups: control (0%), T1 (1%), T2 (3%), and T3 (5%) B. orellana supplementation for 90 days. Edwardsiella tarda was injected intraperitoneally into fish for 14 days after the feeding trial; RPS and histopathological changes was recorded. The result revealed a considerable improvement (P < 0.05) in growth performance (Weight gain, SGR, PER and survival rate) and a decreased feed conversion ratio with increasing BoLM supplementation. However, hematological indices differed significantly among treatments, with T3 showing higher TEC, TLC, hemoglobin, and hematocrit values. Fish Serum biochemical response showed a significant increase, as indicated by total protein, globulin, and albumin in T3 and T2, whereas glucose and cortisol levels were highest in the control group. Histopathological examination revealed distinct tissue alterations in the gills, liver, and intestine among the experimental groups following E. tarda challenge. Furthermore, the treatment group significantly reduced mortality rate following challenges with E. tarda challenge. In conclusion, 5% B. orellana supplementation enhanced growth performance, haemato-biochemical (health) status, and disease resistance in Amur carp.

Indexed as

CarpsEnterobacteriaceae InfectionsFish DiseasesAnimal FeedAnimalsDietDietary SupplementsEdwardsiella tardaPlant LeavesBixa orellanaCyprinus carpio haematopterusDisease resistanceEdwardsiella tardaSerum biochemical

Identifiers

PMID42825947

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.