Evidence map›Paper›PMID 42825936›Full record

ArticlePflugers Archiv : European journal of physiology2026

NS1643 enhances the activity of T1019PfsX38 and Q1070X hERG channels associated with long QT syndrome type 2.

Majid K Al Salmani, Amira Al Kharusi, Mohammed Al Rawahi, Sulayma Albarwani

Abstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Majid K Al SalmaniDepartment of Physiology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman. m.alsalmani1@squ.edu.om.
Amira Al KharusiDepartment of Physiology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Mohammed Al RawahiSultan Qaboos University Hospital, Muscat, Oman.
Sulayma AlbarwaniDepartment of Physiology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.

Funding

Sultan Qaboos University IG/MED/PHYS/24/01
6 · The paper itself

Abstract

Type 2 long QT syndrome (LQT2) increases the risk of cardiac arrest and sudden death due to reduced rapid delayed rectifier potassium currents (IKr) in the heart. Caused by loss-of-function genetic variants in the hERG K

Indexed as

CresolsERG1 Potassium ChannelLong QT SyndromePhenylurea CompoundsAction PotentialsHEK293 CellsHumans1,3-bis(2-hydroxy-5-trifluoromethylphenyl)ureaCresolsERG1 Potassium ChannelKCNH2 protein, humanPhenylurea CompoundsCardiac arrhythmiaHERGKCNH2KV11.1Long QT syndrome

Identifiers

PMID42825936
PMCPMC13633300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.