ArticleClinical oral investigations2026
Modality-specific quantitative radiologic characterization of diffuse sclerosing osteomyelitis of the mandible: a pilot study.
Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDiffuse sclerosing osteomyelitis (DSO) of the mandible is a rare chronic inflammatory disease characterized by recurrent painful swelling and trismus. While advanced stages are known to show radiographically evident bone sclerosis, objective quantitative imaging criteria remain poorly defined. This study aimed to characterize modality-specific radiological features of DSO using intra-individual side-to-side comparison of bone density and cortical thickness. MATERIALS AND
methodsThis single-center retrospective study included 22 patients treated for DSO between 2010 and 2021. Pre-treatment panoramic radiographs were available for all patients, CT datasets for 6 patients, and CBCT for 3 patients. Bone density was quantified using relative grayscale values in panoramic radiography, Hounsfield units (HU) in CT, and gray values in CBCT. Cortical thickness was measured on CT using standardized regions of interest, with contralateral-side comparison. Two blinded observers performed all measurements.
resultsQuantitative analysis demonstrated significantly higher bone density on the affected side in panoramic radiography and CT (panoramic: 46.0 ± 4.0% vs. 39.0 ± 3.6%, p < 0.001; CT: 1220.9 ± 215.8 HU vs. 1108.0 ± 163.9 HU, p = 0.01). In the three available CBCT datasets, descriptively higher gray values were observed on the affected side. CT analysis revealed significantly increased cortical thickness (5.63 ± 0.96 mm vs. 3.86 ± 0.75 mm, p = 0.04). A blurred inferior alveolar nerve canal was consistently observed on panoramic radiographs.
conclusionsQuantitative side-to-side assessment provides an objective radiological description of DSO and may support imaging assessment when interpreted together with clinical and histopathological findings. CLINICAL RELEVANCE: In this selected cohort, DSO-affected regions showed relative densification, cortical thickening in the available CT examinations, and blurring of the inferior alveolar nerve canal on panoramic radiographs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.