Evidence map›Paper›PMID 42825368›Full record

ArticleJournal of global health2026

Equity-focused investment strategies to reduce maternal mortality in the Philippines: a subnational analysis using EQUIST.

Krista Whitley, Polina Lebedeva, Andre Craig Christie, Annabelle Sim, Desere Thompson, Sally Hukpati, Lakshmi Balaji

Abstract read
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Article in Journal of global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Krista WhitleyDepartment of Global and Environmental Health, School of Global Health, New York University, New York, New York, USA.
Polina LebedevaDepartment of Global and Environmental Health, School of Global Health, New York University, New York, New York, USA.
Andre Craig ChristieDepartment of Global and Environmental Health, School of Global Health, New York University, New York, New York, USA.
Annabelle SimDepartment of Global and Environmental Health, School of Global Health, New York University, New York, New York, USA.
Desere ThompsonDepartment of Global and Environmental Health, School of Global Health, New York University, New York, New York, USA.
Sally HukpatiDepartment of Global and Environmental Health, School of Global Health, New York University, New York, New York, USA.
Lakshmi BalajiDepartment of Global and Environmental Health, School of Global Health, New York University, New York, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite sustained national progress in maternal and child health, maternal mortality in the Philippines remains uneven across regions and socioeconomic groups. Women in poor, rural, and conflict-affected areas experience substantially higher maternal mortality than those in higher-income and urban populations. We aimed to assess subnational inequities in maternal mortality and estimate the potential impact and cost-effectiveness of prioritised maternal health interventions in Philippine regions with maternal mortality ratios exceeding the national benchmark. Methods: We conducted an equity analysis and developed an investment case using the UNICEF Equitable Impact Sensitive Tool (EQUIST). Regional maternal mortality ratios were based on 2019 subnational estimates, with the 2017 national maternal mortality ratio used as the benchmark for regional stratification. Intervention effectiveness estimates were drawn from published evidence syntheses and global clinical guidelines, and EQUIST's costing module draws on LiST and the Marginal Budgeting for Bottlenecks approach. Three intervention packages were modelled: upgrading basic and comprehensive emergency obstetric and newborn care facility readiness; ensuring universal availability of uterotonics and magnesium sulphate; and expanding access to modern contraception among adolescents, women from poor households, and high-parity women. Projected maternal deaths averted, disability-adjusted life years averted, and cost per DALY were estimated through 2030. Results: Our modelling suggested that prioritised intervention packages could avert approximately 1,000-2,500 maternal deaths cumulatively through 2030. Facility readiness upgrades were projected to avert 1,000-1,500 maternal deaths, life-saving commodities 1,500-2,000, and modern contraception expansion 2,000-2,500. Sensitivity analysis varying key inputs by ±15% produced corresponding sensitivity ranges of 850-1,750, 1,275-2,300, and 1,700-2,875 maternal deaths averted, respectively. Modern contraception expansion had the lowest modelled cost per DALY averted at approximately US$150, compared with USD 300 for life-saving commodities and USD 450 for facility readiness upgrades. Conclusions: Maternal mortality in the Philippines remains concentrated among disadvantaged subnational populations. Equity-targeted investments, combined with strengthened emergency obstetric care, reliable life-saving commodities, and expanded access to modern contraception, can achieve substantial mortality reductions at highly cost-effective levels.

Indexed as

Health EquityMaternal Health ServicesMaternal MortalityCost-Benefit AnalysisCost-Effectiveness AnalysisFemaleHumansPhilippinesPregnancycost-effectivenessEQUISThealth equitymaternal healthmaternal mortalityPhilippines

Identifiers

PMID42825368
PMCPMC13631932

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