Evidence map›Paper›PMID 42825281›Full record

ArticlePain reports2026

Examining mechanisms connecting child maltreatment and interpersonal violence to young adult pain symptoms in women.

Sarah J Beal, Kim Barnett, Susmita Kashikar-Zuck, Chris King, Constance A Mara, Katie Fox, Mary V Greiner, Jennie G Noll

Abstract read
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In one paragraph

Article in Pain reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarah J BealDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.ORCID https://orcid.org/0000-0002-7223-0070
Kim BarnettDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Susmita Kashikar-ZuckDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Chris KingDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Constance A MaraDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Katie FoxCincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Mary V GreinerDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Jennie G NollUniversity of Rochester, Rochester, NY, USA.

Funding

Preventing Teen Pregnancy: Prepregnancy Psychosocial Mechanisms for at-risk FemalR01HD052533 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI NOLL, JENNIE G · 2007 to 2011
$2.5M
NICHD NIH HHS R01 HD052533
6 · The paper itself

Abstract

Introduction: Child maltreatment has been linked to elevated pain symptoms and more chronic pain in adults. The hypothalamic-pituitary-adrenal (HPA) axis may be a mechanism connecting maltreatment to pain, where early life stressors are thought to impact HPA axis function, leading to increased inflammation and pain. Objectives: This study explored pathways associated with pain in young adult women with and without maltreatment exposure. Maltreatment was expected to be associated with increased exposure to interpersonal violence, inflammation, and negative affect which, in turn, would be associated with more pain in adulthood. Methods: Fifty women randomly selected from a prospective longitudinal cohort (n = 25 with confirmed child maltreatment, n = 25 demographically similar women without history of maltreatment) completed comprehensive assessments of risk factors for pain, including collecting inflammatory biomarkers. Results: Women who had experienced child maltreatment reported more exposure to interpersonal violence as young adults (χ Conclusion: Mechanisms connecting maltreatment to pain are complex. Studies that account for the effect-moderating impact of early life stress on inflammatory pathways alongside psychological effects of stress exposures more proximal to pain (eg, interpersonal violence, mood) are needed.

Indexed as

Adult painChild maltreatmentInterpersonal violenceNegative affect

Identifiers

PMID42825281
PMCPMC13630266

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.