Evidence map›Paper›PMID 42825185›Full record

ArticlePeerJ2026

A large number of variants of

Sunarno Sunarno, Sundari Nursofiah, Novi Amalia, Yudi Hartoyo, Nelly Puspandari, Lisa Andriani Lienggonegoro, Ratih Dian Saraswati, Dwi Febriyana, Tati Febrianti, Khariri Khariri and 10 more

Abstract read
In one paragraph

Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Sunarno SunarnoCenter for Biomedical Research, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Sundari NursofiahCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Novi AmaliaCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Yudi HartoyoCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Nelly PuspandariCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Lisa Andriani LienggonegoroCenter for Biomedical Research, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Ratih Dian SaraswatiCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Dwi FebriyanaCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Tati FebriantiCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Khariri KhaririCenter for Biomedical Research, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Yuni RukminiatiCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Kambang SariadjiCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Masri Sembiring MahaCenter for Biomedical Research, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Yustinus MaladanEijkman Research Center for Molecular Biology, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Ariyani NoviantariCenter for Biomedical Research, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Christina Safira Whinie LestariCenter for Biomedical Research, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Masagus ZainuriCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Pretty MultihartinaCentre for Research and Development of Biomedical and Basic Health of Technology, National Institute of Health Research and Development, Jakarta, Indonesia.
Rahadian PratamaCenter for Biomedical Research, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Siswanto SiswantoHealth Policy Agency, Ministry of Health, Jakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several methods exist for the molecular typing of diphtheria-causing bacteria, including core genome multilocus sequence typing (cgMLST). This study aims to provide an overview of the sequence types, virulence factors, and molecular resistances of Corynebacterium diphtheriae ( Methods: A total of 89 archived isolates of Results: Seventy out of eighty-nine samples qualified for analysis. Fifteen sequence types (STs) were identified: ST377 (24.3%), ST534 (44.3%) and others 31.4%. Approximately 50% of isolates predicted as Gravis biovar, based on Conclusion: This study demonstrates that Indonesia's 2010-2017 diphtheria outbreaks were caused by multiple strains, with ST534 and ST377 being the most prevalent. GC similarity suggests a link or disease transmission between various outbreaks across different regions /islands/countries and periods. ARGs were predominantly associated with phenicol, tetracycline, and sulfonamides resistances; only a few isolates exhibited ARGs linked to penicillin and erythromycin. Our analysis revealed correlations between STs and biovar or resistance profiles. We recommend to implement whole genome sequencing (WGS) for diphtheria surveillance in Indonesia.

Indexed as

Corynebacterium diphtheriaeDiphtheriaDisease OutbreaksAnti-Bacterial AgentsDrug Resistance, BacterialHumansIndonesiaMultilocus Sequence TypingVirulence FactorsAnti-Bacterial AgentsVirulence FactorsCgMLSTCorynebacterium diphtheriaeDiphtheriaDisease outbreaksIndonesia

Identifiers

PMID42825185
PMCPMC13629564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.