ArticleFrontiers in nutrition2026
Nutritional ultrasound cut off for predicting complications and mortality in lung cancer patients: a multicenter longitudinal study from the VALONC project.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Lung cancer remains a leading cause of cancer-related mortality, often exacerbated by malnutrition and muscle depletion that traditional weight-centric metrics may fail to identify. This study assessed the clinical and prognostic relevance of rectus femoris (RF) ultrasound as a practical bedside tool for evaluating muscle-related parameters and clinical outcomes. Methods: This multicenter longitudinal study involved 374 patients (114 females, 260 males) across 10 Spanish hospitals. Researchers performed ultrasonographic assessments of the RF, measuring cross-sectional area (RF-CSA), thickness ( Results: Significant sexual dimorphism was observed; men exhibited larger muscle parameters, while women had higher subcutaneous fat. RF-CSA and RF- Discussion: Rectus femoris ultrasound may provide objective, sex-specific clinical information that complements the GLIM framework and traditional anthropometric assessments. By identifying clinically relevant muscle waste, this bedside tool allows for the early detection of high-risk patients, potentially directing timely nutritional and rehabilitative interventions to improve survival and treatment tolerance in lung cancer.
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