Evidence map›Paper›PMID 42825141›Full record

ArticleRSC advances2026

The improvement of diosmin dissolution by PLGA complexes for oral delivery: physicochemical characterization and anti-inflammatory evaluation.

Anh-Khoa Ton, Truc Thi-Anh Phan, Mi Thi-Tra Tran, Thi-Kim-Chi Huynh, Hoang-Phuc Nguyen, Thi-Cam-Thu Nguyen, Thi-Kim-Dung Hoang

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anh-Khoa TonInstitute of Advanced Technology, Vietnam Academy of Science and Technology, Vietnam No. 1B, Thanh Loc 29 Street, An Phu Dong Ward Ho Chi Minh City 70000 Vietnam hoangthikimdung@gmail.com.ORCID https://orcid.org/0009-0001-0121-5869
Truc Thi-Anh PhanInstitute of Advanced Technology, Vietnam Academy of Science and Technology, Vietnam No. 1B, Thanh Loc 29 Street, An Phu Dong Ward Ho Chi Minh City 70000 Vietnam hoangthikimdung@gmail.com.
Mi Thi-Tra TranFaculty of Applied Science, Ton Duc Thang University No. 19, Nguyen Huu Tho Street, Tan Hung Ward Ho Chi Minh City 70000 Vietnam.
Thi-Kim-Chi HuynhInstitute of Advanced Technology, Vietnam Academy of Science and Technology, Vietnam No. 1B, Thanh Loc 29 Street, An Phu Dong Ward Ho Chi Minh City 70000 Vietnam hoangthikimdung@gmail.com.ORCID https://orcid.org/0000-0002-6214-8022
Hoang-Phuc NguyenInstitute of Advanced Technology, Vietnam Academy of Science and Technology, Vietnam No. 1B, Thanh Loc 29 Street, An Phu Dong Ward Ho Chi Minh City 70000 Vietnam hoangthikimdung@gmail.com.ORCID https://orcid.org/0000-0003-0140-7112
Thi-Cam-Thu NguyenInstitute of Advanced Technology, Vietnam Academy of Science and Technology, Vietnam No. 1B, Thanh Loc 29 Street, An Phu Dong Ward Ho Chi Minh City 70000 Vietnam hoangthikimdung@gmail.com.ORCID https://orcid.org/0000-0001-5458-8012
Thi-Kim-Dung HoangInstitute of Advanced Technology, Vietnam Academy of Science and Technology, Vietnam No. 1B, Thanh Loc 29 Street, An Phu Dong Ward Ho Chi Minh City 70000 Vietnam hoangthikimdung@gmail.com.ORCID https://orcid.org/0000-0002-9369-8051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diosmin (DSN) is a potent flavonoid used for chronic venous insufficiency, but its therapeutic potential is constrained by poor aqueous solubility and low oral bioavailability (BCS Class IV). To overcome these challenges, a hybrid polymeric nanocarrier system comprising poly(lactic-

Identifiers

PMID42825141
PMCPMC13629480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.