Evidence map›Paper›PMID 42825120›Full record

ArticleACS omega2026

HLA-DRB1 Polymorphisms Modulate the Dynamic Compatibility between the Presentation of EBNA1

Levy Bueno Alves, Silvana Giuliatti

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Levy Bueno AlvesDepartment of Genetics, Ribeirão Preto Medical School, University of São Paulo, USP, São Paulo 044021-001, Brazil.ORCID https://orcid.org/0000-0002-0223-8982
Silvana GiuliattiDepartment of Genetics, Ribeirão Preto Medical School, University of São Paulo, USP, São Paulo 044021-001, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) shows a strong genetic association with HLA-DRB1 alleles and a consistent epidemiological association with Epstein-Barr virus (EBV) infection. However, it remains unclear how HLA-DRB1 polymorphisms modulate the presentation of autoantigens and viral antigens potentially involved in cross-reactivity. In this study, peptide-HLA (pHLA) complexes formed by six HLA-DRB1 alleles associated with different MS risk profiles were investigated in interaction with CLIP

Identifiers

PMID42825120
PMCPMC13629357

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.