Evidence map›Paper›PMID 42825052›Full record

ArticleCase reports in psychiatry2026

Rapunzel Syndrome as a Complication of Childhood-Onset Trichotillomania.

Ruchika Darapaneni, Zachary Nobile, Regina Reed, Eduardo Espiridion, John Gurski

Abstract read
In one paragraph

Article in Case reports in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruchika DarapaneniPsychiatry Reading Hospital-Tower Health West Reading Pennsylvaina USA towerhealth.org.ORCID https://orcid.org/0000-0003-2638-8560
Zachary NobileInternal Medicine Reading Hospital-Tower Health West Reading Pennsylvaina USA towerhealth.org.ORCID https://orcid.org/0009-0005-5643-4398
Regina ReedPsychiatry Reading Hospital-Tower Health West Reading Pennsylvaina USA towerhealth.org.ORCID https://orcid.org/0000-0002-6781-3554
Eduardo EspiridionPsychiatry Reading Hospital-Tower Health West Reading Pennsylvaina USA towerhealth.org.ORCID https://orcid.org/0000-0001-8471-5203
John GurskiPsychiatry Reading Hospital-Tower Health West Reading Pennsylvaina USA towerhealth.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Rapunzel syndrome is a rare and potentially life-threatening complication of trichotillomania with trichophagia, characterized by the extension of a gastric trichobezoar into the small intestine. Diagnosis is frequently delayed due to nonspecific presenting symptoms, and management requires both surgical intervention and psychiatric treatment to prevent recurrence. Patient Case: We report the case of a 22-year-old woman with childhood-onset trichotillomania and trichophagia who presented with nonspecific abdominal complaints. Imaging revealed a large intragastric mass, and endoscopy confirmed a dense trichobezoar extending through the pylorus into the duodenum, consistent with Rapunzel syndrome. Endoscopic removal was unsuccessful, and the patient underwent open gastrotomy with intact removal of the mass without complication. Psychiatric evaluation revealed a long history of hairpulling and ingestion behaviors beginning in early childhood, with limited prior psychiatric treatment. Discussion: This case illustrates the cumulative medical risk of untreated chronic, childhood-onset trichotillomania with trichophagia, particularly when hair-ingestion behaviors persist without sustained trichotillomania-specific behavioral treatment. Its contribution to the literature lies in the detailed longitudinal psychiatric characterization of symptom progression and the consideration of comorbid attention-deficit/hyperactivity disorder (ADHD), which may be relevant to the hairpulling and ingestion behaviors themselves through attentional dysregulation, impulsivity, impaired inhibitory control, and automaticity. Conclusion: Rapunzel syndrome represents a severe consequence of chronic hairpulling and ingestion behaviors. Early identification of trichophagia, psychiatric referral, and sustained behavioral treatment are essential to prevent progression to life-threatening complications and to reduce recurrence following surgical intervention.

Indexed as

case reportRapunzel syndrometrichophagiatrichotillomania

Identifiers

PMID42825052
PMCPMC13628702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.