Evidence map›Paper›PMID 42825031›Full record

ArticleRevista costarricense de psicologia : organo oficial del Colegio Profesional de Psicologos de Costa Rica

The role of modern neuroscience in the renaissance of psychedelic research.

Kathryn E Evans, Crystian Massengill, Jonnathan Singh Alvarado

Abstract read
In one paragraph

Article in Revista costarricense de psicologia : organo oficial del Colegio Profesional de Psicologos de Costa Rica. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kathryn E EvansDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center and Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA.
Crystian MassengillDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center and Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-5667-5299
Jonnathan Singh AlvaradoDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

Funding

Tracking and regulation of nicotine dependence in the insular cortexF30DA057823 · NIDA · HARVARD MEDICAL SCHOOL · PI EVANS, KATHRYN ELIZABETH · 2023 to 2025
$149k
NIDA NIH HHS F30 DA057823
6 · The paper itself

Abstract

The primary objective of this review is to highlight the increasing relevance of experimental neuroscience in advancing the mechanistic understanding and translational potential of classic psychedelics and other psychoactive substances of interest. First, we review clinical evidence for the therapeutic potential of psychedelics in the context of depression, anxiety, and addiction. Second, we review recent basic neuroscientific findings regarding the molecular and neural circuit bases of psychedelic action, with a focus on contributions from systems neuroscience. We survey recent advances in experimental neuroscience techniques that are well-poised to advance our mechanistic understanding of psychedelics by identifying the specific brain circuits that contribute to distinct aspects of the psychedelic experience. We end by noting that many promising psychoactive substances are woefully understudied in comparison to the more popular psychedelics. Studying their effects on neural circuits and behavior could be a fruitful and financially feasible direction for burgeoning neuroscience research institutions.

Indexed as

basic neurosciencepsilocybinpsychedelicserotoninsystems neurosciencetranslational neuroscience

Identifiers

PMID42825031
PMCPMC13628893

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.