ReviewFrontiers in veterinary science2026
Nano zinc supplementation in broiler nutrition: current evidence, mechanisms of action, and future perspectives.
Review in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zinc is an essential trace mineral involved in numerous biological processes, including growth, antioxidant defense, immune function, and intestinal integrity in broiler chickens. Optimizing its bioavailability remains an important objective in modern poultry nutrition. Nanotechnology has emerged as a promising strategy to enhance zinc bioavailability while potentially reducing dietary inclusion levels and environmental zinc excretion. Current evidence suggests that nano zinc supplementation may enhance antioxidant capacity, modulate immune responses, support intestinal health, and improve productive performance under specific experimental conditions. Several studies further indicate reduced zinc excretion compared with conventional zinc sources, suggesting potential environmental benefits through lower mineral losses. Furthermore, nano zinc has been proposed as part of nutritional strategies aiming to reduce reliance on antimicrobial use by improving gut health and host resilience. However, direct evidence supporting nano zinc as an alternative to antibiotics under commercial production conditions remains limited. Nano zinc supplementation has also been associated with improvements in intestinal morphology, microbial composition, and barrier function, although the underlying molecular mechanisms remain to be fully elucidated. Despite these promising findings, important knowledge gaps remain regarding optimal particle characteristics, dosage, long-term safety, tissue accumulation, and regulatory acceptance. This review summarizes the current evidence on the biological functions and applications of nano zinc in broiler nutrition, discusses the proposed mechanisms of action, critically evaluates the available literature, and highlights priorities for future research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.