Evidence map›Paper›PMID 42824881›Full record

ArticleJournal of oral microbiology2026

Cross-platform, multi-cohort identification of a caries microbial signature.

Anders Esberg, Daniel Jönsson, Peter Persson, Linda Eriksson, Simon Haworth, Ingegerd Johansson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anders EsbergDepartment of Odontology, Umeå University, Sweden.ORCID https://orcid.org/0000-0002-4430-8125
Daniel JönssonDepartment of Clinical Sciences, Lund University, Malmö, Sweden.ORCID https://orcid.org/0000-0002-5220-633X
Peter PerssonDepartment of Clinical Sciences, Lund University, Malmö, Sweden.ORCID https://orcid.org/0009-0001-7573-3220
Linda ErikssonDepartment of Odontology, Umeå University, Sweden.ORCID https://orcid.org/0009-0004-7264-286X
Simon HaworthDepartment of Odontology, Umeå University, Sweden.ORCID https://orcid.org/0000-0001-7793-7326
Ingegerd JohanssonDepartment of Odontology, Umeå University, Sweden.ORCID https://orcid.org/0000-0002-9227-8434

Funding

Wellcome Trust
6 · The paper itself

Abstract

Objective: To identify a robust salivary microbial signature associated with caries using a cross-platform, multi-cohort design. Design: Full-length 16S rRNA gene sequencing (ONT) and shotgun metagenomics (MET) were performed in a derivation cohort with matched data ( Results: ONT and MET shared community structure despite differences in sequencing depth and detection sensitivity. Inter-individual ecological distances were moderately correlated (Spearman Conclusions: Key ecological features of the oral microbiome are reproducible across sequencing platforms. The microbial signature of caries can be summarised using a detection-based risk score which may have potential uses in caries risk assessment.

Indexed as

cariesdental healthmetagenomicoral microbiomeOxford nanopore sequencingrisk score

Identifiers

PMID42824881
PMCPMC13629774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.