ArticleEJHaem2026
EBV-Positive Sinonasal Plasma Cell Neoplasms: A Case Series With Favorable Outcomes in Elderly Males.
Article in EJHaem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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11 authors.
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Abstract
Introduction: Epstein-Barr virus positive plasma cell neoplasms in immunocompetent hosts typically behave like aggressive lymphomas, often classified as plasmablastic lymphoma. We evaluated six sinonasal neoplasms in elderly males with unusually indolent courses at Mayo Clinic. Methods: A single-center, retrospective review of plasmablastic lymphoma cases identified six cases with unusually favorable outcomes. We analyzed clinical presentations, pathologic features, and treatment outcomes. Results: All patients were male with age range 61-80 years. Five patients had Ann Arbor stage IE disease and one had Stage IV; all lacked B symptoms, and LDH was normal in five. Histologic evaluation revealed mixed mature plasma cell and plasmablastic features in three cases and pure plasmablastic morphology in three. All cases demonstrated EBER and CD138 positivity with monotypic light chain restriction (3 Conclusions: These neoplasms show less aggressive behavior than typical plasmablastic lymphoma, suggesting this sinonasal disease represents a distinct indolent subset of EBV positive PCNs. Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.
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