ArticleFrontiers in surgery2026
Acute appendicitis during pregnancy: a case-control study.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Background: Acute appendicitis is the most common non-obstetric surgical emergency in pregnancy. Diagnosis is difficult due to atypical symptoms, anatomical changes, and limited imaging utility, while delayed diagnosis increases maternal-fetal risks. This study compared clinical, laboratory, imaging and perioperative outcomes between pregnant and non-pregnant women. Methods: This analysis included a multi-centered retrospective case-control study from July 1, 2020 to December 30, 2025. The operative characteristics involved in the pregnancy women were investigated using univariate analyses. Results: There were 99 pregnant women and 186 non-pregnant reproductive-age women underwent surgery enrolled in this research. Pregnant patients had lower right lower quadrant tenderness ( Conclusion: Acute appendicitis in pregnancy presents atypically with lower ultrasound sensitivity. MRI improves diagnostic accuracy. Laparoscopic appendectomy is safe and feasible in pregnancy.
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