ReviewAnesthesiology research and practice2026
Recovery Kinetics and Postoperative Outcomes of Propofol-Based Total Intravenous Anesthesia Versus Sevoflurane in Ambulatory Surgery: A Systematic Review and Meta-Analysis of Randomized Studies.
Review in Anesthesiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
8 authors.
Funding
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Abstract
Background: Optimal anesthetic selection is critical for recovery and patient outcomes in ambulatory surgery. This systematic review and meta-analysis compares propofol-based total intravenous anesthesia (TIVA) with sevoflurane in adults undergoing outpatient procedures, focusing on randomized evidence published since 2014 to reflect contemporary clinical practice. Methods: We performed a PRISMA-compliant, random-effects meta-analysis of 15 randomized controlled trials ( Results: Fifteen RCTs were included. For the primary outcomes, discharge readiness was shorter with TIVA in a single core trial (not a pooled meta-analytic estimate) (mean difference [MD] -5.8 min; 95% confidence interval [CI] -10.63 to -0.97; Conclusions: Contemporary randomized evidence suggests that propofol TIVA may reduce PONV and yield a small reduction in postoperative pain scores. Evidence regarding discharge readiness, PACU LOS, and emergence is limited or inconsistent and does not support a general claim of faster early recovery with either technique. Anesthetic choice should balance these symptomatic effects against patient factors and institutional resources.
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