Evidence map›Paper›PMID 42824459›Full record

ArticleDEN open2027

Flushing-Assisted Saline Immersion Endoscopic Submucosal Dissection in the Rectum: A Video-Based Feasibility Series.

Thomas Matthews, Jonathan Landy, Hiromitsu Ban, Takashi Toyonaga, Noriko Suzuki

Abstract read
In one paragraph

Article in DEN open, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas MatthewsWolfson Unit for Endoscopy, St Mark's The National Bowel Hospital London UK.
Jonathan LandyWolfson Unit for Endoscopy, St Mark's The National Bowel Hospital London UK.
Hiromitsu BanDepartment of Gastroenterology Department of Gastroenterology Omi Medical Center Shiga Japan.
Takashi ToyonagaDivision of Gastroenterology Kobe University Graduate School of Medicine Hyogo Japan.
Noriko SuzukiWolfson Unit for Endoscopy, St Mark's The National Bowel Hospital London UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flushing endoscopic submucosal dissection (ESD) is a refinement of saline immersion ESD in which energy-synchronized saline flushing from the knife tip is hypothesized to disperse micro-bubbles and facilitate more controlled coagulation at the tissue interface. We retrospectively evaluated the technical feasibility of this approach in 10 rectal procedures performed at a tertiary referral center. Complete procedural videos were reviewed to describe treated visible submucosal vessel burden, minor bleeding, episodes of transient loss of visualization, and hemostatic forceps use. En bloc and histologically margin-negative (R0) resection was achieved in all 10 cases, while curative endoscopic resection was achieved in nine cases (90%). No intraprocedural perforation, delayed bleeding, post-ESD coagulation syndrome, or unplanned repeat intervention occurred. Median lesion size was 55 mm (interquartile range, 40-69.5), median procedure duration was 102.5 min (100-167.5), and median treated visible vessel count was 21 (11.5-40.75), corresponding to 1.04 vessels/cm

Indexed as

endoscopic submucosal dissectionhemostasisisotonic solutionsrectal neoplasmsrectumsurgical

Identifiers

PMID42824459
PMCPMC13627967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.