ArticleFrontiers in neuroscience2026
MRI-based lumbar cross-sectional indentation value is associated with spinopelvic sagittal balance in patients with degenerative kyphosis.
Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate whether MRI-based paraspinal muscle morphology, assessed using the lumbar cross-sectional indentation value (LCIV), is associated with spinopelvic sagittal balance in patients with degenerative kyphosis (DK). Methods: This retrospective case-control study included 81 patients with DK, defined as degenerative thoracolumbar kyphosis and/or loss of lumbar lordosis, and 60 surgical controls with symptomatic lumbar spinal stenosis but without degenerative spinal deformity. LCIV was measured from T12-L1 to L4-L5 on axial T2-weighted MRI, and the mean LCIV (mLCIV) was calculated. Spinopelvic sagittal balance in the DK group was evaluated using pelvic incidence minus lumbar lordosis (PI-LL) mismatch and pelvic tilt (PT). Associations among mLCIV, body mass index (BMI), thoracolumbar kyphosis, lumbar lordosis, and PT were also analysed. Results: Patients with DK had a lower mLCIV than controls (7.2 ± 5.4 mm vs. 10.8 ± 3.5 mm, Conclusion: Lower mLCIV was observed in patients with PI-LL mismatch and increased PT, suggesting that lower LCIV may accompany spinopelvic sagittal imbalance and compensatory pelvic retroversion in DK. LCIV may provide a simple MRI-based measure of posterior paraspinal muscle contour in sagittal balance evaluation.
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