Evidence map›Paper›PMID 42824341›Full record

ArticleFrontiers in bioengineering and biotechnology2026

A comparative screening of freshwater and marine microalgae for salinity-induced intracellular mannitol accumulation.

Shibin Nadersha, Ashfaq Ahmad, Syed Salman Ashraf, Jorge Rodríguez

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shibin NadershaDepartment of Chemical and Petroleum Engineering, Khalifa University, Abu Dhabi, United Arab Emirates.
Ashfaq AhmadDepartment of Biological Sciences, Khalifa University, Abu Dhabi, United Arab Emirates.
Syed Salman AshrafDepartment of Biological Sciences, Khalifa University, Abu Dhabi, United Arab Emirates.
Jorge RodríguezDepartment of Chemical and Petroleum Engineering, Khalifa University, Abu Dhabi, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The growing demand for sustainable, low-glycaemic sugar alternatives has increased interest in biological polyol production; however, comparative evaluations of microalgae for salinity-induced intracellular polyol accumulation remain limited. Methods: This study systematically screened two freshwater species ( Results: No detectable intracellular polyols were observed in the freshwater species under any treatment. In contrast, intracellular mannitol accumulated exclusively in the marine species, reaching maximum concentrations of 28 mg g Discussion: These findings demonstrate that intracellular mannitol accumulation is a species-specific response to salinity stress rather than a universal microalgal adaptation. The comparative screening identifies

Indexed as

industrial biotechnologyintracellular polyolmannitolmicroalgaesalinity stress response

Identifiers

PMID42824341
PMCPMC13627334

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.