Evidence map›Paper›PMID 42824198›Full record

ArticleFrontiers in neurology2026

Identification and genotype-phenotype correlation of

P N Sylaja, Rinta Paul, U K Madhusoodanan, Neena S Kumar, Lakshmi J Nair, P Sankara Sarma, Alfiya Fasaludeen, Sunil Kumar, E R Jayadevan, Divya Pachat and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

P N SylajaDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Rinta PaulDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
U K MadhusoodananDepartment of Biochemistry, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Neena S KumarDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Lakshmi J NairDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
P Sankara SarmaDepartment of Public Health, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India.
Alfiya FasaludeenDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Sunil KumarDepartment of Imaging Sciences and Intervention Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
E R JayadevanDepartment of Imaging Sciences and Intervention Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Divya PachatDepartment of Clinical Genetics, Aster MIMS, Calicut, Kerala, India.
Sapna Erat SreedharanDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
B Jayanand SudhirDepartment of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
K H Muneeb HamzaDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
M V Anjana MadhuDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Moinak BanerjeeDepartment of Neurobiology, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: Moyamoya disease is known to be associated with the Ring Finger 213 gene variant ( Methods: The study prospectively enrolled 100 patients with unilateral or bilateral Moyamoya disease (June 2023 to June 2024). Whole exome sequencing was performed to identify all the Results: Seventy-four (74%) patients carried no Conclusion: The study confirmed that both

Indexed as

Adenosine TriphosphatasesMoyamoya DiseaseUbiquitin-Protein LigasesAdolescentAdultCohort StudiesFemaleGenetic Association StudiesHumansIndiaMaleMiddle AgedPhenotypePolymorphism, Single NucleotideProspective StudiesSouth Asian PeopleAdenosine TriphosphatasesRNF213 protein, humanUbiquitin-Protein Ligasesgenotype–phenotype correlationsMoyamoya diseaseRNF213 geneRNF213 p.R4810K variantsingle nucleotide polymorphism

Identifiers

PMID42824198
PMCPMC13627448

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.