Evidence map›Paper›PMID 42824171›Full record

Trial reportFrontiers in neuroscience2026

The impact of an app-delivered mindfulness-based intervention on resting-state functional connectivity in pediatric concussion: a pilot study.

Olivier Brown, Andra Smith, Molly Cairncross, Andrew B Dodd, Gary S Goldfield, Clare Gray, Ashley D Harris, Natalia Jaworska, Bechara J Saab, Veronik Sicard and 4 more

Registry-linked trialAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05105802 (Mindfulness-Based Intervention for Mild Traumatic Brain Injury), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05105802 nacompletednot on this map

Mindfulness-Based Intervention for Mild Traumatic Brain Injury

TypeinterventionalSponsorChildren's Hospital of Eastern OntarioRan2022 to 2024Enrolled99ConditionsConcussion, MildArmsMindfulness-Based Intervention, Cognitive Sham + Usual Care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Olivier BrownChildren's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Andra SmithSchool of Psychology, University of Ottawa, Ottawa, ON, Canada.
Molly CairncrossDepartment of Psychology, Simon Fraser University, Burnaby, BC, Canada.
Andrew B DoddChildren's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Gary S GoldfieldChildren's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Clare GrayDepartment of Psychiatry, University of Ottawa, Ottawa, ON, Canada.
Ashley D HarrisDepartment of Radiology, Hotchkiss Brain Institute, Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada.
Natalia JaworskaSchool of Psychology, University of Ottawa, Ottawa, ON, Canada.
Bechara J SaabMobio Interactive Pte Ltd., Singapore, Singapore.
Veronik SicardChildren's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Noah D SilverbergRehabilitation Research Program, Centre for Aging SMART, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
Lisa A S WalkerSchool of Psychology, University of Ottawa, Ottawa, ON, Canada.
Roger ZemekChildren's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Andrée-Anne LedouxChildren's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rationale: Concussion disrupts brain connectivity, and effective treatments remain limited. Mindfulness-based interventions (MBIs) may influence functional connectivity (FC) of networks affected by concussion, but pediatric trials are lacking. This study investigated whether an app-delivered MBI produced greater FC changes than a sham condition across the default mode (DMN), salience (SN), and central executive (CEN) networks. Methods: This randomized clinical trial (NCT05105802) recruited participants aged 12.00-17.99 years from the emergency department or interdisciplinary concussion clinic, then randomly assigned them to MBI or cognitive sham. Brain imaging sessions occurred at 72 h and 4 weeks post-concussion. Region-of-interest and seed-to-voxel analyses examined Group × Time interactions in FC across DMN, SN, and CEN ( Results: Thirty-six participants were included (MBI: Conclusion: Mindfulness-based intervention training led to changes in FC in networks implicated in concussion recovery. Larger studies are needed to support these findings. Clinical trial registration: https://clinicaltrials.gov/study/NCT05105802, identifier NCT05105802.

Indexed as

concussionfMRIfunctional connectivitymindfulnesspediatric

Identifiers

PMID42824171
PMCPMC13627364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.