Evidence map›Paper›PMID 42823965›Full record

ArticleFrontiers in neurology2026

Association between lactate-to-albumin ratio and in-hospital mortality in ICU patients with acute ischemic stroke: a retrospective cohort study.

Xiaocui Yang, Yue Zhang, Min Ou, Yiwen Liu

Abstract read
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Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Xiaocui YangWest China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yue ZhangWest China Hospital, Sichuan University, Chengdu, Sichuan, China.
Min OuWest China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yiwen LiuWest China Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early risk stratification is critical for critically ill patients with ischemic stroke. The prognostic value of the lactate-to-albumin ratio (LAR) remains unclear in this population. Methods: This single-center retrospective cohort study enrolled adult ICU patients with ischemic stroke from West China Hospital. LAR was calculated using the first lactate and albumin values on ICU admission. Log-transformed LAR was adopted as the main exposure, and the primary outcome was in-hospital mortality. Multivariable logistic regression, ROC analysis, quartile stratification, subgroup, and sensitivity analyses were performed among 749 patients with complete exposure and outcome data, of whom 576 had complete covariate data and comprised the primary multivariable regression cohort. Results: A total of 749 patients were included, with an in-hospital mortality rate of 30.7%. In complete-case multivariable analysis ( Conclusion: Elevated LAR is independently linked to higher in-hospital mortality among critically ill ischemic stroke patients. It may serve as a simple adjunctive marker for early risk stratification.

Indexed as

Hospital MortalityIschemic StrokeLactic AcidSerum AlbuminAgedAged, 80 and overChinaFemaleHumansIntensive Care UnitsMaleMiddle AgedRetrospective StudiesLactic AcidSerum Albuminin-hospital mortalityischemic strokelactate-to-albumin ratiologistic regressionretrospective cohort study

Identifiers

PMID42823965
PMCPMC13626895

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