Evidence map›Paper›PMID 42823964›Full record

ReviewiScience2026

A biomaterials roadmap from retinoic acid biology to kidney regenerative therapy.

Ru-Yu Tan, Li-Li Huang, Qin-Ying She, Yun-Ci Ma, Min-Hong Liu, Li-Juan Li, Chao Zhang, Yi-Wen Zhong, Shan Zhou, Hui-Xin Bi

Abstract readReview
In one paragraph

Review in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ru-Yu TanDepartment of Nephrology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Li-Li HuangDepartment of Nephrology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Qin-Ying SheDepartment of Nephrology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Yun-Ci MaDepartment of Nephrology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Min-Hong LiuDepartment of Nephrology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Li-Juan LiDepartment of Nephrology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Chao ZhangDepartment of Nephrology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Yi-Wen ZhongDepartment of Nephrology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Shan ZhouDepartment of Nephrology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.
Hui-Xin BiDepartment of Nephrology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mammalian kidney cannot generate new nephrons after birth, a key driver of chronic kidney disease progression toward end-stage renal disease. Retinoic acid (RA) is an evolutionarily conserved morphogen essential for kidney development, and its signaling is reactivated after injury to coordinate repair-yet this endogenous repair program is transient and insufficient to guide the kidney along the regenerative continuum toward

Indexed as

biomaterialsdevelopmental bioinspirationmultifunctional scaffoldsnanocarriersrenal regenerationretinoic acid

Identifiers

PMID42823964
PMCPMC13626926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.