ArticleHerz2026
Correlation of carotid intima-media thickness and lipid indices with SYNTAX score in coronary artery disease: a cross-sectional study.
Article in Herz, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCarotid intima-media thickness (CIMT) is a widely used noninvasive marker of subclinical atherosclerosis, yet its relationship with angiographic coronary disease complexity, quantified with the SYNTAX score, remains incompletely characterized. This study evaluated the correlations between CIMT, low-density lipoprotein cholesterol (LDL-C), the Atherogenic Index of Plasma (AIP), and SYNTAX score in patients with angiographically confirmed coronary artery disease (CAD) in coastal South India.
methodsA total of 115 consecutive patients with proven CAD undergoing elective coronary angiography (≥ 50% stenosis) were enrolled. B‑mode ultrasonography was used to measure CIMT bilaterally. Lipid profiles were obtained from fasting samples, and AIP was computed as log(TG/HDL-C). Pearson correlations, ANOVA, and multivariate logistic regression were used for analysis.
resultsMean CIMT was positively correlated with both SYNTAX score (r = 0.192, p = 0.039) and LDL‑C (r = 0.207, p = 0.026). SYNTAX scores increased progressively across single-, double-, and triple-vessel disease groups (F = 25.50, p < 0.001). There was no significant association between AIP and either CIMT or SYNTAX score. Inter-rater agreement for SYNTAX score categorization was excellent (Cohen's κ = 0.880, 95% confidence interval [CI]: 0.799-0.960, p < 0.001). On multivariate analysis, only age independently predicted high-complexity CAD (OR = 1.661, 95% CI: 1.077-2.561, p = 0.022).
conclusionThe SYNTAX score increased significantly with increasing vessel involvement, and CIMT was modestly correlated with SYNTAX score and LDL‑C. Age was the sole independent predictor of high-complexity CAD. These preliminary findings suggest that CIMT may have potential as a supplementary marker of coronary complexity, but this requires confirmation in larger, prospective studies before any clinical application can be recommended.
Indexed as
Identifiers
42823489What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.