Evidence map›Paper›PMID 42823451›Full record

ArticleNature communications2026

SLC4A7/NBCn1 maintains intracellular pH to support mTORC1 activity and antibody-secreting cell differentiation.

Ke Hu, Yin-Hu Wang, Anthony Y Tao, Maxwell McDermott, Miki Jishage, Li Zhong, Thomas Boehringer, Marcus J Hines, Sergei B Koralov, Ebbe Boedtkjer and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ke Hu *Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Yin-Hu Wang *Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-3637-8852
Anthony Y Tao *Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Maxwell McDermottDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Miki JishageDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Li ZhongDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Thomas BoehringerDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-4289-7931
Marcus J HinesDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Sergei B KoralovDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-4843-3791
Ebbe BoedtkjerDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-5078-9279
Stefan FeskeDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA. stefan.feske@nyulangone.org.ORCID 0000-0001-5431-8178

Funding

U.S. Department of Health & Human Services | National Institutes of Health (NIH) AI097302U.S. Department of Health & Human Services | National Institutes of Health (NIH) AI175276
6 · The paper itself

Abstract

Antibody-producing plasmablasts (PB) and plasma cells (PC) are critical for humoral immunity, autoimmunity and vaccine responses. Despite the importance of environmental stressors in regulating humoral immune responses, the influence of pH on PB and PC differentiation remains elusive. Here, we identify SLC4A7/NBCn1, a Na

Indexed as

Antibody-Producing CellsCell DifferentiationMechanistic Target of Rapamycin Complex 1Sodium-Bicarbonate SymportersAnimalsAntibody FormationB-LymphocytesHydrogen-Ion ConcentrationImmunity, HumoralInfluenza A virusMiceMice, Inbred C57BLMice, KnockoutPlasma CellsMechanistic Target of Rapamycin Complex 1Sodium-Bicarbonate Symporters

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.