Evidence map›Paper›PMID 42823434›Full record

ReviewPediatric research2026

Life after the NICU: targeting modifiable factors to improve neurodevelopmental outcomes in children born extremely preterm.

Rhandi Christensen, Daniela Salvo, Kathryn Y Manning, Tricia Williams, Mehmet N Cizmeci

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In one paragraph

Review in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rhandi ChristensenDepartment of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada. rhandi.christensen@sickkids.ca.
Daniela SalvoDepartment of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Kathryn Y ManningSickKids Research Institute, Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Tricia WilliamsDepartment of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada.
Mehmet N CizmeciDepartment of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infants born preterm are at risk for neurodevelopmental delays and impairments, with the greatest risk for those born extremely preterm or at the limits of viability. Developmental surveillance in neonatal neurodevelopmental follow-up programs is essential for infants born preterm as it allows for early identification of developmental delays and referral to intervention services. Previous studies have identified modifiable home and environmental factors that can alter the neurodevelopmental trajectory of children born preterm. In this review, we discuss how targeting modifiable factors can improve outcomes in the most vulnerable infants born extremely preterm or at the limits of viability. We present The 6 Ps to Promote Positive Neurodevelopmental Outcomes in Prematurity, including post-discharge follow-up in neonatal neurodevelopmental programs, providing enriched environments, physical environment, parent education, parenting style and parent wellness. As parents prepare to go home from the NICU they are faced with uncertainty about their child's future outcomes. Parents often ask, "what can we do for our baby?" We provide evidence-informed recommendations for counseling families during the transition home to enable parents to actively participate in optimizing their child's neurodevelopmental outcomes. IMPACT: Targeting modifiable home and environmental factors may improve neurodevelopmental outcomes in infants born extremely preterm. This article presents The 6 Ps to Promote Positive Neurodevelopmental Outcomes in Prematurity: post-discharge follow-up in neonatal neurodevelopmental programs, providing enriched environments, physical environment, parent education, parenting style and parent wellness. During the transition from NICU to home, parents should be counseled on these modifiable factors and encouraged to actively participate in optimizing their child's neurodevelopmental outcomes.

Identifiers

PMID42823434

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.