ArticleRadiological physics and technology2026
Interfractional variability and reproducibility of accumulated dose in cervical cancer radiotherapy associated with bladder volume.
Article in Radiological physics and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Pelvic anatomical variations during radiotherapy for cervical cancer may alter delivered dose distributions, affecting target coverage and organ-at-risk (OAR) sparing. This study evaluated interfractional dose variability and the impact of bladder volume on accumulated dose delivery in patients treated with helical tomotherapy. A retrospective analysis of ten cervical cancer patients treated with helical tomotherapy was performed. Accumulated doses were generated using Accuray PreciseART via deformable registration of planning computed tomography (pCT) and daily MVCT images. Percentage dose deviations between planned and accumulated doses were analyzed using paired t-tests, while differences among three bladder volume groups were evaluated using linear mixed-effects models. Accumulated PTV doses were significantly lower than planned, with the greatest reduction in D
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