ArticleJournal of ophthalmic inflammation and infection2026
Salmonella associated endogenous endophthalmitis: a case study and review of literature.
Article in Journal of ophthalmic inflammation and infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo report a rare case of bilateral endogenous endophthalmitis caused by Salmonella Paratyphi A in an immunocompetent patient and to review the relevant literature.
methodBrief report.
resultsA 23-year-old woman presented with acute bilateral vision loss over one day. She had previously received systemic corticosteroids for a presumed Vogt-Koyanagi-Harada syndrome and was administered oral steroids. At presentation, examination revealed conjunctival congestion, Descemet's folds, fibrinous anterior chamber reaction, and hypopyon in the left eye, with obscured; fundus details. B-scan ultrasonography demonstrated a thickened retinochoroidal complex with shallow choroidal detachments and anechoic vitreous cavities. Blood culture grew Salmonella Paratyphi A and vitreous cytology showed abundant monocytes. She received intravitreal vancomycin (1 mg/0.1 ml) and ceftazidime (2.25 mg/0.1 ml), IV ceftriaxone 2 g/day guided by susceptibility, topical prednisolone acetate 1% and atropine 1%, and a tapering course of oral steroids. Following resolution of anterior segment inflammation, she underwent pars plana vitrectomy with lensectomy and silicone oil endotamponade in both eyes. Postoperatively, best-corrected visual acuity improved to 20/250 (OD) and 20/200 (OS).
conclusionWhile Salmonella-associated endogenous endophthalmitis is typically associated with poor visual outcomes, this bilateral Paratyphi A case demonstrates that prompt recognition and aggressive combined medical and surgical management can achieve meaningful visual recovery.
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