ArticleAbdominal radiology (New York)2026
Photon-counting detector CT for follow-up after TACE in hepatocellular carcinoma: effects of reconstruction kernel and sharpness.
Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo compare the performance of different reconstruction kernels and sharpness levels in photon-counting detector CT (PCD-CT) for post-transarterial chemoembolization (TACE) imaging of hepatocellular carcinoma (HCC), with particular emphasis on residual viable tumor conspicuity, and to identify reconstruction settings that may improve clinical follow-up assessment.
methodsIn this retrospective study, 72 patients with HCC undergoing TACE were included. Triple-phase contrast-enhanced CT images were reconstructed using body regular (Br) and quantitative regular (Qr) kernels at four different sharpness levels (36, 40, 44, and 48). Quantitative analysis included image noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and edge sharpness. Subjective image quality was assessed by two readers using a 5-point Likert scale.
resultsIncreasing kernel sharpness significantly increased image noise and decreased SNR and CNR across all contrast-enhanced phases (e.g., arterial phase, Br kernel, noise 16.8 ± 2.1 to 36.1 ± 4.2; CNR
conclusionReconstruction kernel type and sharpness level significantly influence quantitative and subjective image quality in post-TACE PCD-CT of HCC. Optimized reconstruction kernel and sharpness settings may improve residual viable tumor conspicuity and facilitate lesion assessment.
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