Evidence map›Paper›PMID 42820616›Full record

ArticleJACC. Case reports2026

Transcatheter Tricuspid Valve Replacement for Torrential Tricuspid Regurgitation in Complex Adult Congenital Heart Disease.

Emily Morris, Ali Roomi, Massimiliano Costello, Russell Franks, Joanna Lim, Saul Myerson, James D Newton, Elizabeth Orchard, Sam Dawkins, Thomas J Cahill

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emily MorrisOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom; Green Templeton College, University of Oxford, Oxford, United Kingdom.
Ali RoomiOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.
Massimiliano CostelloOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.
Russell FranksOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.
Joanna LimOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.
Saul MyersonOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.
James D NewtonOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.
Elizabeth OrchardOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.
Sam DawkinsOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.
Thomas J CahillOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom. Electronic address: tom.cahill@ouh.nhs.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere tricuspid regurgitation (TR) carries high morbidity and is often undertreated in patients with complex congenital heart disease and prohibitive surgical risk. CASE SUMMARY: A 33-year-old woman with complex congenital heart disease and multiple prior surgeries presented with progressive right-sided heart failure and torrential TR. Imaging demonstrated septal leaflet splinting by a transvenous pacing lead. She was unsuitable for surgery or transcatheter edge-to-edge repair. Following Heart Team assessment, transcatheter tricuspid valve replacement with a 48 mm EVOQUE valve (Edwards Lifesciences) was performed. Despite procedural challenges including delivery system septal bias, implantation was successful with mild residual TR and early symptomatic improvement. DISCUSSION: Transcatheter tricuspid valve replacement is an emerging option for high-risk patients. This case demonstrates feasibility in complex congenital anatomy with pacing leads, a group under-represented in current evidence. TAKE-HOME MESSAGES: Transcatheter tricuspid valve replacement expands treatment options in high-risk congenital tricuspid regurgitation. Careful imaging and Heart Team planning are essential for success.

Indexed as

congenital heart diseaseEVOQUETTVR

Identifiers

PMID42820616
PMCPMC13643562

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.