ArticleJACC. Case reports2026
End-Diastolic Forward Flow Through the Pulmonic Valve in Carcinoid Heart Disease.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEnd-diastolic forward flow (EDFF) through the pulmonic valve is classically described after repaired tetralogy of Fallot and is usually attributed to restrictive right ventricular (RV) physiology. Its significance in carcinoid pulmonic valve disease is less established. CASE SUMMARY: We describe 6 patients with carcinoid heart disease and pulmonic valve involvement referred for operative management. Perioperative echocardiography demonstrated late-diastolic antegrade flow through the pulmonic valve after atrial activation and before ventricular systole, consistent with EDFF during atrial contraction. All patients underwent pulmonic and tricuspid valve replacement; additional left-sided valve surgery, coronary bypass, septal closure, or pulmonary artery/RV outflow tract patch augmentation was performed when indicated. DISCUSSION: EDFF in carcinoid heart disease likely reflects organized atrial contraction, severe tricuspid and pulmonic regurgitation, altered RV diastolic properties, and incomplete pulmonic valve closure. Electrocardiography-Doppler correlation is required to avoid misclassification and underestimation of pulmonic regurgitation severity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.