Evidence map›Paper›PMID 42820609›Full record

ArticleJACC. Case reports2026

First Reported Native Transcatheter Tricuspid Valve Replacement in Congenitally Corrected Transposition of the Great Arteries.

John T D'Angelo, Karan Sud, Nikoloz Shekiladze, Joel T Hardin, Nikoloz Koshkelashvili, Patrick T Gleason, Adam B Greenbaum, Vasilis C Babaliaros

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

John T D'AngeloDivision of Cardiology, Emory Structural Heart and Valve Center, Emory University Hospital Midtown, Atlanta, Georgia, USA.
Karan SudDivision of Cardiology, Emory Structural Heart and Valve Center, Emory University Hospital Midtown, Atlanta, Georgia, USA.
Nikoloz ShekiladzeDivision of Cardiology, Emory Structural Heart and Valve Center, Emory University Hospital Midtown, Atlanta, Georgia, USA.
Joel T HardinDivision of Cardiology, Emory Adult Congenital Heart Disease Center, Emory University Hospital, Atlanta, Georgia, USA.
Nikoloz KoshkelashviliKaring Hearts Cardiology, Johnson City, Tennessee, USA.
Patrick T GleasonDivision of Cardiology, Emory Structural Heart and Valve Center, Emory University Hospital Midtown, Atlanta, Georgia, USA.
Adam B GreenbaumDivision of Cardiology, Emory Structural Heart and Valve Center, Emory University Hospital Midtown, Atlanta, Georgia, USA.
Vasilis C BabaliarosDivision of Cardiology, Emory Structural Heart and Valve Center, Emory University Hospital Midtown, Atlanta, Georgia, USA. Electronic address: vbabali@emory.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCongenitally corrected transposition of the great arteries (CC-TGA) can lead to severe systemic tricuspid regurgitation (TR). There is limited evidence on transcatheter tricuspid valve replacement (TTVR) in these patients. CASE SUMMARY: A 59-year-old woman with CC-TGA presented with symptomatic severe systemic TR. She was at high risk for surgery, and transcatheter interventions were considered by our heart team. TTVR on the systemic tricuspid valve was performed using a Sapien M3 valve (Edwards Lifesciences), and the systemic TR was eliminated. There were no complications, with significant symptomatic improvement at the 30-day follow-up. DISCUSSION: Transcatheter therapies in high-surgical risk adult CC-TGA patients are being increasingly investigated. This case shows that TTVR using a Sapien M3 valve is feasible in CC-TGA patients with symptomatic severe systemic TR. TAKE-HOME MESSAGE: TTVR with the Sapien M3 valve is a feasible and safe alternative in high-surgical risk CC-TGA patients with symptomatic systemic TR.

Indexed as

congenital heart defecttransposition of the great arteriestricuspid valvevalve replacement

Identifiers

PMID42820609
PMCPMC13643539

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