Evidence map›Paper›PMID 42820474›Full record

ArticleChemistry & biodiversity2026

tris-Schiff Base Derivatives Containing Flurbiprofen as Potential Tyrosinase Inhibitors: Synthesis, In Vitro Evaluation, Molecular Docking, DFT and Dynamics Simulations.

Aftab Alam, Muhammad Ayaz, Zainab, Majid Khan, Ahmed A Elhenawy, Najeeb Ur Rehman, Sajjad Ur Rahman, Mumtaz Ali, Ahmed Al-Harrasi, Manzoor Ahmad

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aftab AlamDepartment of Chemistry, Rawalpindi Women University, Rawalpindi, Pakistan.
Muhammad AyazDepartment of Chemistry, University of Malakand, Pakistan.
ZainabCollege of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang, China.
Majid KhanCollege of Chemistry, Fuzhou University, Fuzhou, China.
Ahmed A ElhenawyChemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
Najeeb Ur RehmanNatural and Medical Sciences Research Center, University of Nizwa, Oman.
Sajjad Ur RahmanDepartment of Chemistry, University of Malakand, Pakistan.
Mumtaz AliDepartment of Chemistry, University of Malakand, Pakistan.
Ahmed Al-HarrasiNatural and Medical Sciences Research Center, University of Nizwa, Oman.
Manzoor AhmadDepartment of Chemistry, University of Malakand, Pakistan.ORCID https://orcid.org/0000-0001-9736-5900

Funding

Higher Education Commission of Pakistan 14622
6 · The paper itself

Abstract

A novel series of tris-Schiff bases of flurbiprofen has been synthesised via multi-step reactions, structures were deduced by means of HR-ESI-MS,

Indexed as

Density Functional TheoryEnzyme InhibitorsFlurbiprofenMolecular Docking SimulationMonophenol MonooxygenaseMolecular Dynamics SimulationMolecular StructureSchiff BasesStructure-Activity RelationshipEnzyme InhibitorsFlurbiprofenMonophenol MonooxygenaseSchiff BasesDFTdynamics simulationsflurbiprofenin vitro tyrosinasemolecular dockingstructure activity relationshiptris‐Schiff bases

Identifiers

PMID42820474
PMCPMC13629248

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.