Evidence map›Paper›PMID 42820352›Full record

ReviewThe breast journal2026

Lower-Cost Nonsurgical Primary Prevention Strategies for Women at High Risk of Breast Cancer: A Scoping Review.

Menghua Wen, Youfu Zhao, Chunying He

Abstract readScoping ReviewReview
In one paragraph

Review in The breast journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Menghua WenYan'an Medical College, Yan'an University, Yan'an, Shaanxi, China, yau.edu.cn.ORCID https://orcid.org/0009-0006-6038-751X
Youfu ZhaoYan'an Medical College, Yan'an University, Yan'an, Shaanxi, China, yau.edu.cn.ORCID https://orcid.org/0009-0000-9377-9073
Chunying HeMedical Oncology, Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China, yau.edu.cn.ORCID https://orcid.org/0009-0006-3664-4782

Funding

Natural Science Foundation of Shaanxi Province 2025JC-YBMS-835Science and Technology Development Research Project of Affiliated Hospital of Yan'an University 2022PT-26Yan'an Bureau of Science and Technology 2023-SFGG-055Yan'an Science and Technology Innovation Team Project 41
6 · The paper itself

Abstract

backgroundA systematic mapping of nonsurgical, lower-cost primary prevention strategies for women at high risk of breast cancer remains limited.

objectiveTo identify and summarize lower-cost (i.e., lower economic cost relative to surgical and pharmaceutical alternatives; not dependent on expensive equipment, patented drugs, or complex medical procedures; implementable through community, family, or self-management models), nonsurgical primary prevention strategies for women at high risk of breast cancer, providing empirical evidence to inform clinical practice, health education, and public health policy.

methodsFollowing the Joanna Briggs Institute (JBI) methodology for scoping reviews and the Participants, Concept, and Context (PCC) framework, we systematically searched 9 Chinese and English databases. Search terms covered "breast cancer," "high-risk women," "primary prevention," and various nonsurgical strategies. Two independent reviewers performed literature screening and data extraction.

resultsSeventeen studies were included, and six prevention strategy categories were identified: nutritional dietary interventions, physical activity interventions, comprehensive lifestyle interventions, chemoprevention, digital health interventions, and health education with self-management. Comprehensive lifestyle intervention emerged as the core strategy with robust evidence and manageable costs. Nutritional interventions have shifted from single nutrients to overall dietary patterns. Chemoprevention, limited by cost and side effects, is more suitable for very high-risk women. Digital health interventions and health education offer advantages in medically underserved areas.

conclusionThis scoping review systematically maps lower-cost, nonsurgical primary prevention strategies for women at high risk of breast cancer, identifying six categories of promotable interventions. Comprehensive lifestyle intervention represents the most evidence-supported and economically manageable core strategy. For the first time from the dual perspectives of "nonsurgical" and "lower cost," this review provides practical references for primary healthcare systems, clinical education, and public health policy, with particular relevance for resource-limited settings.

Indexed as

Breast NeoplasmsPrimary PreventionFemaleHumansLife Stylebreast cancercostnonsurgical treatmentprimary preventionscoping review

Identifiers

PMID42820352
PMCPMC13628707

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.