Evidence map›Paper›PMID 42820187›Full record

ArticleJU open plus2026

Effect of Acupuncture on Urine Production and Storage in Prostate Cancer Survivors With Nocturia: Exploratory Analysis of a Randomized Clinical Trial.

Allison G Booher, Jake Mao, Jaspreet Sandhu, Divya Ajay, Sigrid V Carlsson, Vincent Laudone, Michael J Morris, Kevin T Liou

Abstract read
In one paragraph

Article in JU open plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Allison G BooherDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID https://orcid.org/0009-0001-5935-4773
Jake MaoDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID https://orcid.org/0009-0007-5152-8293
Jaspreet SandhuDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Divya AjayDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Sigrid V CarlssonClinical Epidemiology of Early Cancer Detection, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID https://orcid.org/0000-0003-3553-5710
Vincent LaudoneDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Michael J MorrisDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID https://orcid.org/0000-0002-9454-0096
Kevin T LiouDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID https://orcid.org/0000-0002-2438-9749

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Acupuncture for Cognitive Health in Older Survivors of Prostate Cancer (ACHIEVE)K08CA266927 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Kevin T Liou · 2022 to 2026
$1.2M
NCI NIH HHS K08 CA266927NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Background: Nocturia is multifactorial condition, but most treatments only target urine production or storage in isolation. Acupuncture has been shown to decrease nocturia, but its mechanisms remain unclear. This study explores the preliminary effects of acupuncture on urine production and storage to inform future mechanistic hypotheses. Methods: We conducted a secondary analysis of 3-day frequency volume charts from a clinical trial in which prostate cancer survivors with nocturia were randomized to receive acupuncture or usual care (waitlist control [WLC]). Within-group posttreatment changes and between-group differences were compared by paired and two-sample t-tests in the total sample and in subgroups stratified by the presence of nocturnal polyuria at baseline. Results: In the total sample (N = 35), acupuncture reduced nocturia episodes (-1.1 vs -0.4, Conclusions: Among prostate cancer survivors with nocturia, acupuncture demonstrated joint effects on urine production and storage. Acupuncture also reduced nocturia across different types of underlying urinary dysfunction, including nocturnal polyuria. If confirmed, these preliminary findings could inform a novel treatment approach uniquely suited for the multifactorial etiology of nocturia.

Indexed as

acupunctureintegrative medicinelower urinary tract symptomsnocturiaprostate cancer

Identifiers

PMID42820187
PMCPMC13626574

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.