Evidence map›Paper›PMID 42820168›Full record

ArticleAnnual review of cancer biology2026

Beyond Mice and Men: Alternative Vertebrate and Invertebrate Models in Cancer Biology.

David Bilder

Abstract read
In one paragraph

Article in Annual review of cancer biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

David BilderDepartment of Molecular and Cell Biology, University of California, Berkeley, California, USA.

Funding

Polarity, growth, and morphogenesis of epitheliaR35GM130388 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI David Bilder · 2019 to 2026
$6.5M
Mechanisms of Drosophila Tumor SuppressionR01GM090150 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID · 2010 to 2018
$2.0M
PQ6 MECHANISMS OF CACHEXIA LIKE WASTING IN A DROSPHILA CANCER MODELR21CA180107 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID · 2013 to 2014
$281k
NCI NIH HHS R21 CA180107NIGMS NIH HHS R01 GM090150NIGMS NIH HHS R35 GM130388
6 · The paper itself

Abstract

While cancer looms large in the public and scientific minds, this can result in a quite narrow view of its range and manifestations. The centering of human clinical investigations and the popularity of mouse models leave many unaware of fascinating findings about cancer in other species. Comparative oncology shows that cancer can be found not just in mammals but widely across the tree of animals, a realization that broadens views of the disease in fundamentally important ways. Examples include protective mechanisms of cancer-resistant species, transmissible cancers, and questions about whether cancer risk is intrinsic to metazoan life. I highlight strong evidence for cancer in invertebrates, focusing on

Indexed as

cancercomparative oncologyDrosophilainvertebratetumortumor–host

Identifiers

PMID42820168
PMCPMC13626269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.