Evidence map›Paper›PMID 42820011›Full record

ArticleChemical & biomedical imaging2026

Pathogen-Specific PET Imaging of Pulmonary Infection Using [

Spenser R Simpson, Tyler Simmons, Haley Echlin, Shyra Wilde, Shashika S Perera, Paulina Villanueva, Amy Iverson, Amber Schuster, Peter Vogel, Amanda Green and 2 more

Abstract read
In one paragraph

Article in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Spenser R SimpsonDepartment of Radiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.ORCID https://orcid.org/0000-0001-9731-8354
Tyler SimmonsDeparment of Host Microbe Interactions, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Haley EchlinDeparment of Host Microbe Interactions, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Shyra WildeDeparment of Host Microbe Interactions, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Shashika S PereraDepartment of Radiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Paulina VillanuevaDepartment of Radiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Amy IversonDeparment of Host Microbe Interactions, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Amber SchusterDepartment of Radiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Peter VogelComparative Pathology Core, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Amanda GreenDeparment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.ORCID https://orcid.org/0009-0006-2250-2687
Jason RoschDeparment of Host Microbe Interactions, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Kiel D NeumannDepartment of Radiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.ORCID https://orcid.org/0000-0001-9093-3522

Funding

[18F]fluoromannitol: A novel imaging agent to delineate osteomyelitis in sickle cell diseaseR01AI192221 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Amanda Marie Green, Kiel Neumann · 2025 to 2026
$1.8M
Novel pro-drug imaging agents to detect neuroinflammation in Alzheimer's DiseaseR01AG093113 · NIA · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Chia-Yi Kuan, Kiel Neumann · 2026 to 2026
$759k
NIAID NIH HHS R01 AI192221NIA NIH HHS R01 AG093113
6 · The paper itself

Abstract

Pneumonia remains a leading cause of global morbidity and mortality, with diagnostic uncertainty frequently complicating clinical management, particularly in patients with chronic lung disease, immunocompromise, or healthcare-associated infections. Conventional imaging modalities and microbiologic testing lack specificity for distinguishing bacterial pneumonia from viral infection, sterile inflammation, or noninfectious lung disease, often resulting in empiric antibiotic overuse and delayed alternative therapies. In this study, we evaluated [

Indexed as

F18fluoromannitolinfectionPETpneumoniapulmonaryradiotracer

Identifiers

PMID42820011
PMCPMC13625748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.