Evidence map›Paper›PMID 42819996›Full record

ArticleChemical & biomedical imaging2026

Donor-Acceptor Bridging via Twisted Quasi-Double-Bond: A Facile Design Strategy for Typical NIR-II AIEgen with "Simple" Structure.

Chunbin Li, Jen-Shyang Ni, Pengfei Zhang, Daoyong Jiang, Jianguo Wang, Kai Li, Shuang-Quan Zang, Ryan T K Kwok, Weihong Tan, Ben Zhong Tang

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In one paragraph

Article in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chunbin LiDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, State Key Laboratory of Nervous System Disorder, Division of Life Science, and Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Kowloon, Hong Kong 999077, China.
Jen-Shyang NiDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.ORCID https://orcid.org/0000-0002-6727-2401
Pengfei ZhangDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, State Key Laboratory of Nervous System Disorder, Division of Life Science, and Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Kowloon, Hong Kong 999077, China.ORCID https://orcid.org/0000-0003-0390-3806
Daoyong JiangSchool of Chemistry and Life Sciences, Guilin Normal University, Guilin 541199, China.
Jianguo WangCollege of Chemistry and Chemical Engineering, College of Biomedical Sciences, Inner Mongolia Key Laboratory of Synthesis and Application of Organic Functional Molecules, Inner Mongolia University, Hohhot 010021, China.ORCID https://orcid.org/0000-0003-0984-9716
Kai LiCollege of Chemistry and Molecular Engineering, Zhengzhou University, Science Road No. 100, Zhengzhou 450001, China.ORCID https://orcid.org/0000-0001-9458-4796
Shuang-Quan ZangCollege of Chemistry and Molecular Engineering, Zhengzhou University, Science Road No. 100, Zhengzhou 450001, China.ORCID https://orcid.org/0000-0002-6728-0559
Ryan T K KwokDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, State Key Laboratory of Nervous System Disorder, Division of Life Science, and Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Kowloon, Hong Kong 999077, China.ORCID https://orcid.org/0000-0002-6866-3877
Weihong TanHangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.ORCID https://orcid.org/0000-0002-8066-1524
Ben Zhong TangDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, State Key Laboratory of Nervous System Disorder, Division of Life Science, and Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Kowloon, Hong Kong 999077, China.ORCID https://orcid.org/0000-0002-0293-964X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A facile design strategy for NIR-II fluorophores with aggregation-induced emission (AIE) characteristics was presented. This kind of NIR-II AIE luminogen, TSPCI is an example, is by the strong acceptor-donor bridging via a twisted quasi-double-bond (TQDB). Theoretical calculations revealed that the introduction of TQDB was the major factor for quenching of the photoexcited TSPCI molecule in the solution state. TSPCI showed excellent NIR-II imaging performance for in vivo dynamic imaging with high contrast and penetration depth. TSPCI holds great potential as a building block to easily fabricate activatable fluorescent probes with superior responsive ability in the second NIR optical window for in vivo imaging applications.

Indexed as

acceptor−donor bridgingaggregation-induced emissionfluorescent probesin vivo imagingnear-infrared II

Identifiers

PMID42819996
PMCPMC13625704

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