Evidence map›Paper›PMID 42819980›Full record

ArticleFrontiers in oral health2026

Expected clinical and patient-centered outcomes associated with different rehabilitation strategies for severe maxillary atrophy: an international cross-sectional survey.

Giulio Gasparini, Mattia Todaro, Edoardo Papa, Marco Gaetano Amato, Paolo De Angelis, Alessandro Moro, Carlo Lajolo, Gianluca Nicolai, Edoardo Rella, Roberto Boniello and 14 more

Abstract read
In one paragraph

Article in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Giulio GaspariniPre-prosthetic Surgery Unit, Fondazione Policlinico Agostino Gemelli IRCCS Hospital, Rome, Italy.
Mattia TodaroMaxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, Rome, Italy.
Edoardo PapaDepartment of Emergency and Acceptance, UOSD Maxillofacial Surgery, University of Rome Tor Vergata, Rome, Italy.
Marco Gaetano AmatoMaxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, Rome, Italy.
Paolo De AngelisDepartment of Head and Neck, Oral Surgery and Implantology Unit, Institute of Clinical Dentistry, Catholic University of the Sacred Heart, Polyclinic Foundation, Rome, Italy.
Alessandro MoroMaxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, Rome, Italy.
Carlo LajoloHead and Neck Department, "Fondazione Policlinico Universitario A. Gemelli-IRCCS," School of Dentistry, Università Cattolica del Sacro Cuore, Rome, Italy.
Gianluca NicolaiDepartment of Emergency and Acceptance, UOSD Maxillofacial Surgery, University of Rome Tor Vergata, Rome, Italy.
Edoardo RellaDepartment of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS-Università Cattolica del Sacro Cuore, Rome, Italy.
Roberto BonielloMaxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, Rome, Italy.
Xavier Moix GilMaxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, Rome, Italy.
Edoardo StaderiniIRCCS, Fondazione Policlinico Universitario Agostino Gemelli, Roma, Italy.
Sofia GaspariniPre-prosthetic Surgery Unit, Fondazione Policlinico Agostino Gemelli IRCCS Hospital, Rome, Italy.
Federico PerquotiMaxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, Rome, Italy.
Gianmarco SpinozziMaxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, Rome, Italy.
Veronica SantoroDivision of Maxillo-Facial Surgery, Department of Medicine, Surgery and Dentistry, ASST Santi Paolo e Carlo Hospital, University of Milan, Milan, Italy.
Daniele Di CarloMaxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, Rome, Italy.
Giuliano AscaniDepartment of Maxillofacial Surgery, Spirito Santo Hospital, Pescara, Italy.
Paolo Francesco ManiconeDivision of Prosthodontics-Institute of Clinical Dentistry, Department of Neuroscience, Sensory Organs and Chest, Fondazione Policlinico Universitario A. Gemelli-IRCCS, School of Dentistry, Universita' Cattolica del Sacro Cuore., Roma, Italy.
Maurizio Diego ForestiMaxillo-Facial Surgery Unit, Ospedale SS. Trinità, Cagliari, Italy.
Maurizio PeruginiDepartment of Maxillo Facial Surgery, Santa Rosa Hospital Viterbo, Viterbo, Italy.
Francesca AzzuniMaxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, Rome, Italy.
Collaborative Working Group
Gianmarco SaponaroMaxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe maxillary atrophy remains one of the most challenging conditions in implant dentistry and maxillofacial surgery. Multiple rehabilitation strategies are currently available, including regenerative procedures, alternative implant-based approaches, and hybrid concepts. Although clinical outcomes have been widely reported, limited information exists regarding clinician-reported expectations associated with different rehabilitation strategies when evaluating the same clinical scenario. The aim of this study was to investigate clinician-reported expectations associated with different rehabilitation approaches for severe maxillary atrophy. Materials and methods: An international cross-sectional survey was conducted using a standardized anonymized CBCT case classified as Cawood and Howell Class VI. The questionnaire was distributed through professional and academic networks between July and November 2025. Respondents with experience in at least five complex implant-prosthetic rehabilitations per year were included. After selecting their preferred rehabilitation strategy, participants completed a branching questionnaire exploring clinician-reported expectations regarding safety, predictability, immediate loading, implant survival, treatment duration, smile satisfaction, masticatory function, oral hygiene and maintainability, postoperative morbidity, annual maintenance costs, patient satisfaction, and quality-of-life improvement. Descriptive statistics were performed. Results: A total of 155 eligible clinicians from 33 countries were included. Alternative implant-based strategies were selected by 83 respondents (53.5%), regenerative approaches by 45 (29.0%), and hybrid approaches by 27 (17.4%). Clinicians selecting alternative implant-based strategies more frequently anticipated immediate loading (81.9%), functional rehabilitation within 72 h (83.1%), and implant survival exceeding 95% at five years (57.8%). Respondents selecting regenerative approaches more commonly expected treatment durations of approximately one year (64.4%) and reported highly favorable expectations regarding smile satisfaction (86.7%), patient satisfaction (82.2%), and quality-of-life improvement (97.8%). Across all therapeutic preference groups, clinician-reported expectations regarding masticatory function, patient satisfaction, and quality-of-life improvement were generally favorable. Most respondents anticipated postoperative discomfort lasting between one and four weeks and treatment abandonment rates below 5%. Conclusions: Clinicians selecting different rehabilitation strategies for severe maxillary atrophy reported distinct expectations regarding treatment timing, predictability, implant survival, aesthetics, maintenance requirements, morbidity, and patient-centered outcomes. Despite these differences, expectations were generally favorable across all therapeutic preference groups, suggesting that multiple rehabilitation pathways are currently perceived as viable treatment options. The findings should be interpreted as clinician-reported expectations rather than direct measurements of clinical or patient-reported outcomes.

Indexed as

bone graftingCawood and Howell Class VIclinician preferencespatient-specific implants (PSI)pterygoid implantssevere maxilla atrophytreatment decision—makingzygomatic implants

Identifiers

PMID42819980
PMCPMC13625680

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.