Evidence map›Paper›PMID 42819979›Full record

ArticleChemical & biomedical imaging2026

Tetrahedral DNA Framework-Bridged Aptasensing Method for Ultrasensitive Determination of Cardiac Troponin I.

Jiaqi Cai, Wenshuai Zhou, Liang Gao, Xiaolin Yang, Meng Li, Chengxiao Zhang, Honglan Qi

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Article in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jiaqi CaiKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.
Wenshuai ZhouKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.
Liang GaoXi'an People's Hospital (Xi'an Fourth Hospital), Xi'an, 710068, P. R. China.
Xiaolin YangKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.ORCID https://orcid.org/0000-0002-3420-3215
Meng LiKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.
Chengxiao ZhangKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.ORCID https://orcid.org/0000-0003-2829-5122
Honglan QiKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.ORCID https://orcid.org/0000-0002-2268-0073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of a sensitive and accurate method for the determination of cardiac troponin I (cTnI), as an ideal biomarker of acute myocardial infarction (AMI), is critical for the early diagnosis of AMI. In this work, a tetrahedral DNA framework (TDF)-bridged aptasensing method was proposed for the ultrasensitive determination of cTnI via electrogenerated chemiluminescence (ECL) and fluorescence imaging methods, in which a specific anti-cTnI aptamer-tagged tetrahedral DNA framework (TDF-aptamer) was designed as a capture probe by incorporating a specific aptamer against cTnI within the three-dimensional TDF. The TDF-aptamer was modified onto a gold electrode surface through the Au-S bond, providing a specifically captured platform for cTnI with a 3D binding space at the nanoscale. One microsized signal probe (Ab2-biotin•SA@MB-Ru1) was synthesized by using magnetic Fe

Indexed as

aptasensingcardiac troponin Ielectrogenerated chemiluminescencefluorescenceimagingtetrahedral DNA framework

Identifiers

PMID42819979
PMCPMC13625694

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.