Evidence map›Paper›PMID 42819763›Full record

ArticleHealth science reports2026

Association of Serum Vitamin D Level and Hematological Inflammatory Indices in Participants of the MASHAD Study.

Abbas Mohtashamian, MohammadReza Latifi, Reza Nejad Shahrokh Abadi, Rana Kolahi-Ahari, Toktam Sahranavard, Sara Saffar Soflaei, Negar Morovatdar, Mohaddeseh Sedaghati Noghabi, Gordon A Ferns, Ramin Rezaee and 1 more

Abstract read
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abbas MohtashamianDepartment of Nutritional Sciences, Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0003-2695-3072
MohammadReza LatifiDepartment of Biology Islamic Azad University, Mashhad Branch Mashhad Iran.
Reza Nejad Shahrokh AbadiLeipzig Center of Metabolism (LeiCeM), Leipzig University, Leipzig, Germany Leipzig University, Leipzig, Germany Leipzig Germany.ORCID https://orcid.org/0000-0003-1283-1066
Rana Kolahi-AhariApplied Biomedical Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-3681-7528
Toktam SahranavardApplied Biomedical Research Center Mashhad University of Medical Sciences Mashhad Iran.
Sara Saffar SoflaeiInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0001-6795-0623
Negar MorovatdarMashhad University of Medical Sciences Iran.
Mohaddeseh Sedaghati NoghabiApplied Biomedical Research Center Mashhad University of Medical Sciences Mashhad Iran.
Gordon A FernsDivision of Medical Education Brighton and Sussex Medical School Brighton UK.ORCID https://orcid.org/0000-0002-0957-8349
Ramin RezaeeApplied Biomedical Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0001-7567-6142
Majid Ghayour-MobarhanMetabolic Syndrome Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-1081-6754

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Vitamin D, a fat-soluble vitamin, has various vital roles in physiological processes. Recent evidence suggests that optimal vitamin D levels may be associated with improved immune function and reduced systemic inflammation. The present study aims to evaluate associations between serum vitamin D levels and various hematological inflammatory indices in participants of the MASHAD cohort study, Mashhad, Iran. Methods: This study was designed as a cross-sectional analysis conducted within the framework of phase I of the MASHAD cohort study. Participants (aged ≥ 18 years old and signed an informed consent) were recruited from a defined population, ensuring the representativeness of the sample for evaluation of potential association between serum vitamin D levels and hematological inflammatory indices including Red Cell Distribution Width (RDW-CV), high-sensitivity C-reactive protein (hs-CRP), systemic immune-inflammation index (SII), platelet-to-lymphocyte ratio (PLR), Neutrophil-to-Lymphocyte Ratio (NLR), Mean Platelet Volume (MPV), and Platelet Distribution Width (PDW). Results: A total of 458 participants were included in the current study, comprising 229 males and 229 females. Serum vitamin D had weak correlation with hs-CRP ( Conclusion: The current findings revealed a weak association between serum vitamin D concentrations and inflammatory indicators. Among hematological parameters, gender-based differences were observed, with PDW and RDW levels significantly varying between vitamin D quartiles in women.

Indexed as

hematologic inflammatory biomarkersinflammatory indicesmetabolic parametersvitamin D

Identifiers

PMID42819763
PMCPMC13624846

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.