Evidence map›Paper›PMID 42819691›Full record

ArticleClinical case reports2026

Potential Benefit of Ruxolitinib in Suspected Ocular and Neurological Transplant-Associated Thrombotic Microangiopathy After Allogeneic Stem Cell Transplantation: A Case Report and Review.

Lise-Marie Pillet, Antoine Arandilla, Gaëtan Sauvetre, Paul Goupillou, Adrien Lefevre, Maximilien Grall, Antoine Bonnevalle, Bertrand Bourre, Dominique Penther, Sophie Porcheron and 4 more

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lise-Marie PilletDepartment of Hematology Centre Henri Becquerel Rouen France.
Antoine ArandillaOphthalmology Department Charles Nicolle University Hospital Rouen France.
Gaëtan SauvetreDepartment of Internal Medicine Rouen University Hospital Rouen France.
Paul GoupillouOphthalmology Department Charles Nicolle University Hospital Rouen France.
Adrien LefevreOphthalmology Department Charles Nicolle University Hospital Rouen France.
Maximilien GrallIntensive Care Unit Charles Nicolle University Hospital Rouen France.
Antoine BonnevalleNeurology Department Charles Nicolle University Hospital Rouen France.
Bertrand BourreNeurology Department Charles Nicolle University Hospital Rouen France.
Dominique PentherDepartment of Genetic Oncology Centre Henri Becquerel Rouen France.
Sophie PorcheronDepartment of Hematology Centre Henri Becquerel Rouen France.
Fabrice JardinDepartment of Hematology Centre Henri Becquerel Rouen France.
Mustafa AlaniDepartment of Hematology Centre Henri Becquerel Rouen France.
Sydney DuboisDepartment of Hematology Centre Henri Becquerel Rouen France.
Vincent CamusDepartment of Hematology Centre Henri Becquerel Rouen France.ORCID https://orcid.org/0000-0002-1559-007X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a rare case of suspected delayed-onset TA-TMA with ocular and neurological involvement following allo-HSCT. The condition was refractory to standard therapies; neurological improvement was temporally associated with ruxolitinib initiation, suggesting a possible GVHD overlap. This report supports a multidisciplinary approach to complex post-transplant endothelial injury and supports further investigation of JAK inhibition in selected cases.

Indexed as

allogeneic stem cell transplantationPurtscher‐like retinopathyruxolitinibtransplant associated thrombotic microangiopathy

Identifiers

PMID42819691
PMCPMC13624534

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.