ArticleDermatology research and practice2026
An Amharic Version of the Children's Dermatology Life Quality Index (CDLQI): Cross-Cultural Adaptation and Psychometric Evaluation.
Article in Dermatology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Skin diseases are associated with reduced health-related quality of life (HRQoL) of children and their families. The Children's Dermatology Life Quality Index (CDLQI) questionnaire is a skin disease-specific measure of HRQoL in children. Our study aimed to translate the CDLQI into Amharic, culturally adapt, and evaluate the validity and reliability of the translation. Methods: This study was embedded within a larger hospital-based cohort study of cutaneous leishmaniasis (CL). Forward-backward translation procedures were conducted, followed by assessment of content and face validity. The psychometric properties were evaluated through reliability (internal consistency and interrater reliability), construct validity (including known-group, convergent, and discriminant validity), and responsiveness to change. Cronbach's alpha, intraclass correlation coefficient (ICC), Mann-Whitney Results: The CDLQI showed acceptable content validity with a modified kappa between 0.7 and 0.9. In a pilot testing, children reported that the items in the translated Amharic version of the CDLQI were unambiguous. Among 188 enrolled participants, 129 (68.62%) were diagnosed with CL and 59 (31.38%) with other skin conditions. The median CDLQI score was 7 (IQR = 10). The overall Cronbach's alpha and ICC were 0.82 and 0.92, respectively. The median CDLQI score showed statistically significant differences between "mild" vs. "severe" and "moderate" vs. "severe" CL cases ( Conclusions: Our Amharic version of the CDLQI showed acceptable validity and reliability, supporting its use in clinical practice and research to assess the HRQoL of Amharic-speaking children with skin conditions in Ethiopia.
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