Evidence map›Paper›PMID 42819430›Full record

ArticleFrontiers in medicine2026

Short-term efficacy and safety of CO

Tingting Su, Yi Yu, Fang Chen, Hongwei Zhang, Lu Zhang, Qing Cong, Long Sui, Limei Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tingting Su *Cervical Diseases Center, Obstetrics and Gynecology Hospital of Fudan University, Yangtze River Delta Integration Demonstration Zone (QingPu), Shanghai, China.
Yi Yu *Perianal Clinic, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Fang ChenPerianal Clinic, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Hongwei ZhangPerianal Clinic, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Lu ZhangPerianal Clinic, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Qing CongCervical Diseases Center, Obstetrics and Gynecology Hospital of Fudan University, Yangtze River Delta Integration Demonstration Zone (QingPu), Shanghai, China.
Long Sui *Cervical Diseases Center, Obstetrics and Gynecology Hospital of Fudan University, Yangtze River Delta Integration Demonstration Zone (QingPu), Shanghai, China.
Limei Chen *Cervical Diseases Center, Obstetrics and Gynecology Hospital of Fudan University, Yangtze River Delta Integration Demonstration Zone (QingPu), Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the short-term efficacy, safety, and human papillomavirus (HPV) clearance outcomes of carbon dioxide (CO Methods: A retrospective cohort study was conducted on 99 patients who underwent CO Results: Among 99 enrolled patients, 7 were lost to follow-up, leaving 92 cases for final analysis. With a mean follow-up of 9.96 months, the overall 3-month treatment response rate was 85.9% (79/92), and the high-risk HPV clearance rate was 70.7% (65/92). No severe complications such as anal stenosis, incontinence, or mucosal erosion were observed during follow-up. Only 5 cases (5.4%) developed mild perianal redness, which resolved with topical antibiotics. Multivariate logistic regression identified preoperative HPV16/18 infection (OR = 3.62, 95% CI: 1.41-9.28, Conclusion: CO

Indexed as

anal intraepithelial neoplasiacarbon dioxide laserhigh-resolution anoscopyhigh-risk HPVlaser vaporization

Identifiers

PMID42819430
PMCPMC13624097

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.