Evidence map›Paper›PMID 42819381›Full record

ArticleFrontiers in rehabilitation sciences2026

Effects of an outpatient pulmonary rehabilitation program on exercise capacity, muscle fatigue, dyspnea, and functional status in post-COVID-19 patients: non-randomized clinical trial.

Miriã C Oliveira, Paolo Capodaglio, Heren N C Paixão, Adriano L Fonseca, Larissa R Alves, Jairo B S Ribeiro Júnior, Rodrigo F Oliveira, Tiago V Fernandes, Daniel G Marconi, Rodrigo A C Andraus and 6 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in rehabilitation sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04982042 (Outpatient and Home Pulmonary Rehabilitation Program for Post COVID-19 Patients), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04982042 naunknown statusnot on this map

Outpatient and Home Pulmonary Rehabilitation Program for Post COVID-19 Patients

TypeinterventionalSponsorCentro Universitário de AnapolisRan2021 to 2022Enrolled40ConditionsCovid19, COVID-19 Respiratory Infection, Lung Diseases, Respiratory InsufficiencyArmsPulmonary Rehabilitation
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Miriã C OliveiraHuman Movement and Rehabilitation Graduate Programn (PPGMHR), Evangelical University of Goiás (UNIEVANGELICA), Anápolis, Brazil.
Paolo CapodaglioResearch Laboratory for Biomechanics, Orthopaedic Rehabilitation Unit, Rehabilitation and Ergonomics, Ospedale San Giuseppe, Milan, Italy.
Heren N C PaixãoHuman Movement and Rehabilitation Graduate Programn (PPGMHR), Evangelical University of Goiás (UNIEVANGELICA), Anápolis, Brazil.
Adriano L FonsecaHuman Movement and Rehabilitation Graduate Programn (PPGMHR), Evangelical University of Goiás (UNIEVANGELICA), Anápolis, Brazil.
Larissa R AlvesHealth Sciences Graduate Program (PPGCS), Faculty of Medical Sciences (FCMSCSP), Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil.
Jairo B S Ribeiro JúniorHealth Sciences Graduate Program (PPGCS), Faculty of Medical Sciences (FCMSCSP), Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil.
Rodrigo F OliveiraHuman Movement and Rehabilitation Graduate Programn (PPGMHR), Evangelical University of Goiás (UNIEVANGELICA), Anápolis, Brazil.
Tiago V FernandesHealth Sciences Graduate Program (PPGCS), Faculty of Medical Sciences (FCMSCSP), Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil.
Daniel G MarconiDepartment Rehabilitation, Barretos Cancer Hospital, Barretos, São Paulo, Brazil.
Rodrigo A C AndrausHuman Movement and Rehabilitation Graduate Programn (PPGMHR), Evangelical University of Goiás (UNIEVANGELICA), Anápolis, Brazil.
Deise A A P OliveiraHuman Movement and Rehabilitation Graduate Programn (PPGMHR), Evangelical University of Goiás (UNIEVANGELICA), Anápolis, Brazil.
Claudia S OliveiraHuman Movement and Rehabilitation Graduate Programn (PPGMHR), Evangelical University of Goiás (UNIEVANGELICA), Anápolis, Brazil.
Carlos H M SilvaHealth Sciences Graduate Program (PPGCS), Faculty of Medical Sciences (FCMSCSP), Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil.
Orlando A GuedesDentistry Graduate Program (PPGO), Evangelical University of Goiás (UNIEVANGELICA), Anápolis, Brazil.
Wilson R Freitas JúniorHealth Sciences Graduate Program (PPGCS), Faculty of Medical Sciences (FCMSCSP), Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil.
Luis V F OliveiraHuman Movement and Rehabilitation Graduate Programn (PPGMHR), Evangelical University of Goiás (UNIEVANGELICA), Anápolis, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: COVID-19 may lead to persistent sequelae that impair functional capacity, resulting in dyspnea, fatigue, and limitations in activities of daily living. Objective: To evaluate exercise capacity, fatigue, dyspnea, and functional status in patients following hospitalization for COVID-19 who underwent an outpatient pulmonary rehabilitation program (PRP). Methods: The study was approved by the Research Ethics Committee of UniEVANGÉLICA (approval number 4,296,707; September 24, 2020) and registered at ClinicalTrials.gov (Identifier: NCT04982042). This prospective single-arm non-randomized clinical trial included symptomatic individuals after COVID-19 infection. Exercise capacity was assessed using the Six-Minute Walk Test, muscle fatigue using the Fatigue Severity Scale (FSS), modified Medical Research Council (mMRC) Dyspnea Scale, and functional status using the Post-COVID-19 Functional Status Scale (PCFS). The PRP consisted of cardiorespiratory training and muscle strengthening exercises performed three times per week for six weeks. Results: A total of 54 patients were included (29 in the Ward Group and 25 in the ICU Group). After the PRP, 6MWT distance increased from 428.52 ± 104.5 m to 503.19 ± 98.04 m ( Conclusion: The outpatient PRP was associated with significant improvements in exercise capacity, fatigue, dyspnea, and functional status. Lower baseline exercise capacity predicted greater improvement, regardless of ICU admission.

Indexed as

COVID-19dyspneaexercise capacityfatiguefunctional statuspulmonary rehabilitation

Identifiers

PMID42819381
PMCPMC13623915

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.