ReviewChemical & biomedical imaging2026
Mechanisms and Applications of Photocatalytic Proximity Labeling.
Review in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Photocatalytic proximity labeling (PPL) is a light-controlled technique for spatially and temporally precise mapping of biomolecular interactions. This review classifies PPL platforms into small-molecule catalysts (transition metal complexes and organic chromophores) and genetically encoded photosensitizers, detailing their mechanisms and biological applicationsfrom subcellular proteomics, cell-cell interface tagging to in vivo labeling. We compare PPL with enzyme-catalyzed methods, highlighting its advantages in spatiotemporal control, minimal genetic manipulation, and suitability for primary cells. Current challenges in PPL are also discussed. As PPL methodologies continue to evolve from mechanistic innovation toward essential biological problem-solving, they hold great promise for elucidating dynamic interaction networks with unprecedented resolution in living systems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.