Evidence map›Paper›PMID 42819325›Full record

ArticleCureus2026

Pore Orientation Affects the Compression Resistance of Unidirectional Porous Beta-Tricalcium Phosphate Wedges in Opening-Wedge High Tibial Osteotomy.

Shinya Kawahara, Takeshi Shimoto, Satoshi Hamai, Yukio Akasaki, Taishi Sato, Yasuharu Nakashima

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Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Shinya KawaharaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JPN.
Takeshi ShimotoDepartment of Information and System Engineering, Faculty of Information Engineering, Fukuoka Institute of Technology, Fukuoka, JPN.
Satoshi HamaiDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JPN.
Yukio AkasakiDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JPN.
Taishi SatoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JPN.
Yasuharu NakashimaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnidirectional porous beta-tricalcium phosphate is used as a synthetic bone substitute in opening-wedge high tibial osteotomy. Because this material has anisotropic mechanical properties, the orientation of its interconnected pores may influence initial support within the osteotomy gap. This study evaluated whether pore orientation affects the compression resistance of unidirectional porous beta-tricalcium phosphate wedges in an opening-wedge high tibial osteotomy-like loading model. MATERIALS AND

methodsThis in vitro biomechanical study evaluated two wedge sizes: WA08, corresponding to an approximately 7.6-degree wedge, and WA14, corresponding to an approximately 14.3-degree wedge. For each size, three configurations were tested: the commercially preformed wedge with pores parallel to the medial and lateral faces, a processed block with pores perpendicular to the lower surface, and a processed block with pores perpendicular to the upper surface. Ten specimens were tested per configuration. Monotonic compression was applied using a hinged fixture that reproduced the geometry of an opening-wedge high tibial osteotomy gap. Load-displacement and nominal contact pressure-displacement curves were compared by pairwise comparisons at each 0.01 mm displacement increment.

resultsIn WA08, the commercially preformed configuration showed greater resistance at larger displacements, with significant differences from the lower-surface and upper-surface perpendicular configurations beginning at 0.37 and 0.41 mm, respectively. In WA14, the commercially preformed and upper-surface perpendicular configurations showed higher load-displacement and nominal pressure-displacement responses than the lower-surface perpendicular configuration.

conclusionsPore orientation affected the initial compression behavior of unidirectional porous beta-tricalcium phosphate wedges in a simulated opening-wedge high tibial osteotomy gap. The commercially preformed configuration showed the most consistent resistance across wedge sizes, suggesting that pore orientation should be considered when selecting or shaping beta-tricalcium phosphate wedges for opening-wedge high tibial osteotomy.

Indexed as

artificial bonebeta-tricalcium phosphatebiomechanicsbone substitutecompression testinghigh tibial osteotomyopening-wedge osteotomypore orientation

Identifiers

PMID42819325
PMCPMC13625615

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.