Evidence map›Paper›PMID 42819043›Full record

ArticleFrontiers in oncology2026

Impact of a multimodal prehabilitation program on postoperative recovery in patients undergoing total laparoscopic hysterectomy and its clinical effects on reducing the risk of venous thromboembolism occurrence.

Liuhua Qu, Ling Yang, Lu Li

Abstract read
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Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Liuhua QuDepartment of Gynaecology, Ningyuan County People's Hospital, Yongzhou, Hunan, China.
Ling YangDepartment of Gynaecology, Ningyuan County People's Hospital, Yongzhou, Hunan, China.
Lu LiDepartment of Gynaecology, Ningyuan County People's Hospital, Yongzhou, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Postoperative recovery and venous thromboembolism (VTE) are major concerns following total laparoscopic hysterectomy (TLH). This study aimed to evaluate the impact of a multimodal prehabilitation program on postoperative recovery and its clinical effects on reducing VTE risk in patients undergoing TLH. Methods: This retrospective study involved 274 patients who underwent TLH for benign uterine diseases. Patients were divided into a conventional group (n = 145) and a prehabilitation group (n = 129). Postoperative recovery indicators, Caprini risk scores, lower extremity deep vein thrombosis (DVT) incidence, serum markers (coagulation function and inflammatory parameters), and complications were compared between groups. Results: Compared with the conventional group, patients in the prehabilitation group demonstrated significantly shorter times to first anal exhaust (22.63 ± 4.38 vs. 24.47 ± 5.44 h, P = 0.002), first bowel movement (61.08 ± 6.23 vs. 63.26 ± 7.21 h, P = 0.008), first ambulation (18.45 ± 3.74 vs. 22.34 ± 4.09 h, P < 0.001), and postoperative hospital stay (4.39 ± 0.71 vs. 6.95 ± 1.03 days, P < 0.001). Postoperative pain scores at 6, 24, and 48 h were also significantly lower in the prehabilitation group (all P < 0.05). Additionally, the prehabilitation group showed improved postoperative Caprini risk profiles (P < 0.001) and significantly lower incidence of lower-extremity DVT (2.33% vs. 14.48%, P < 0.001). Coagulation function and inflammatory markers were also significantly improved in the prehabilitation group. Multivariate analysis further identified the prehabilitation program as an independent protective factor against postoperative DVT (OR = 0.223, 95%CI: 0.099-0.502, P < 0.001). Conclusion: Multimodal prehabilitation significantly enhances postoperative recovery and reduces the risk of venous thromboembolism in patients undergoing TLH.

Indexed as

enhanced recovery after surgeryhysterectomylaparoscopypostoperative complicationsvenous thromboembolism

Identifiers

PMID42819043
PMCPMC13623566

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.